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  • 1
    ISSN: 1437-1596
    Keywords: Serum groups, ORM-phenotyping ; Bloodstains, orosomucoid (ORM) typing ; Orosomucoid typing ; Serumgruppen, ORM-Typisierung ; Blutspuren, Orosomucoid (ORM)-Typen ; Orosomucoid-Typen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Bei 168 nicht verwandten Deutschen wurden die Orosomucoid (ORM)-Typen mittels isoelektrischer Fokussierung und Printimmunfixation untersucht. Zwei neue Allele, vorläufig ORM1*14 and ORM2*13, wurden beobachtet. Die Isoelektrofokussierungs-Methode wurde mit Erfolg zur ORM1-Typisierung an Blutspuren angewandt. Jeder Phänotyp konnte an bis 130°C, bis zu 30 min erhitzten Blutspuren sicher nachgewiesen werden. Die Resultate zeigen, daß der ORM1-Polymorphismus ein neues und aussagekräftiges genetisches Merkmalsystem für die Serumgruppen-Typisierung an Blutspuren ist.
    Notes: Summary The genetic polymorphism of serum orosomucoid (ORM) was studied in 168 unrelated German individuals using isoelectric focusing followed by immunoprinting. Two new alleles, tentatively designated ORM1*14 and ORM2*13, were identified. The method was successfully applied to demonstrate ORM1 types in dried bloodstains. Each type of ORM1 was also correctly determined in bloodstains heated at 130°C for 30 min. The results indicated that ORM1 is a new powerful genetic marker system for the grouping of bloodstains.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 112 (1998), S. 72-74 
    ISSN: 1437-1596
    Keywords: Key words Multiplex STR profiling ; Automated DNA sequencer ; Romany (Gypsy) population ; Population ; genetics ; Hungary
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Abstract A population study of Hungarian Romanies was carried out on the STR loci HumLPL, HumF13B, HumFES and HumF13A01. There was little evidence for association of alleles within/between the four STR systems. Allele frequency distributions were significantly different between the Romany and the previously reported Central Hungarian population databases. Population differentiation was estimated by computing F- and º-statistics as well as frequency estimate differences of individual phenotypes for these two population samples. The results suggest that the population structure may have an effect on the interpretation of forensic DNA evidence in Hungary. Phylogenetic tree reconstruction with six populations from three major ethnic groups revealed a relatively distant genetic relationship of the Baranya Romanies with other Caucasian populations.
    Type of Medium: Electronic Resource
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