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  • Polymer and Materials Science  (3)
  • B chain of oxidized insulin  (2)
  • Capsaicin  (2)
  • Gastric mucosal aspartic proteinase  (2)
Source
Material
Years
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Proteolytic activity and cleavage specificity of cathepsin E at the physiological pH as examined towards the B chain of oxidized insulin
    Amsterdam : Elsevier
    FEBS Letters 292 (1991), S. 53-56 
    Details
    ISSN: 0014-5793
    Keywords: B chain of oxidized insulin ; Cathepsin E ; Cleavage specificity ; Gastric mucosal aspartic proteinase ; Nph ; PAGE ; Proteolytic activity ; SDS ; cya ; cysteic acid ; nitrophenylalanine ; polyacrylamide gel electrophoresis ; sodium dodecyl sulfate
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0014-5793(91)80832-N
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Proteolytic activity and cleavage specificity of cathepsin E at the physiological pH as examined towards the B chain of oxidized insulin
    Amsterdam : Elsevier
    FEBS Letters 292 (1991), S. 53-56 
    Details
    ISSN: 0014-5793
    Keywords: B chain of oxidized insulin ; Cathepsin E ; Cleavage specificity ; Gastric mucosal aspartic proteinase ; Proteolytic activity
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0014-5793(91)80832-N
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Effect of the tachykinin receptor antagonists, SR 140333, FK 888, and SR 142801, on capsaicin-induced mouse ear oedema (1996)
    Springer
    Inflammation research 45 (1996), S. 303-307 
    Details
    ISSN: 1420-908X
    Keywords: Capsaicin ; Mouse ear oedema ; Tachykinin receptor antagonist ; SR 140333
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We examined the effect of SR 140333, a nonpeptide NK1 receptor antagonist, FK 888, a peptide NK1 antagonist, and SR 142801, a non-peptide NK3 antagonist, on ear oedema induced by topical application of capsaicin (250 μg/ear) in mice. SR 140333 (ED50: 39 μg/kg, i.v.) dose-dependently inhibited the oedema response to capsaicin, whereas FK 888 (1.0 mg/kg, i.v.) and SR 142801 (3.0 mg/kg, i.v.) had no effect. Furthermore, SR 140333 significantly (p〈0.001) suppressed ear oedema in response to intradermal injection of substance P (SP) (100 pmol/site) by i.v. administration (0.1 mg/kg), and co-injection (50 pmol/site). In contrast, FK 888 (1.0 mg/kg, i.v. and 500 pmol/site) was ineffective in the response to SP. The present results suggest that the difference in effects of the two NK1 receptor antagonists on the oedema response to capsaicin is due to species differences in affinities for the NK1 receptor in the mouse skin. Moreover, it seems unlikely that the NK3 receptor is involved primarily in capsaicin-induced mouse ear oedema.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02280996
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Involvement of substance P as a mediator in capsaicin-induced mouse ear oedema (1995)
    Springer
    Inflammation research 44 (1995), S. 470-474 
    Details
    ISSN: 1420-908X
    Keywords: Mouse ear oedema ; Capsaicin ; Tachyphylaxis ; Substance P ; NK1 receptor antagonist
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We examined the involvement of substance P (SP) in mouse ear oedema induced by topical application of capsaicin (250 µg/ear). Reapplication of capsaicin at 4h, 24h, and 48h after initial treatment did not induce a second oedema response. Oedema induced after the second application was significantly (p〈0.01 orp〈0.001) suppressed for up to 30 days but was observed when capsaicin was applied 40 days after initial treatment. Topical pretreatment of ears with capsaicin at 4h, 24h and 48h before i.v. injection of SP (5 µg/kg) did not cause a significant inhibition of plasma extravasation in ear skin. NK1 receptor antagonists such as RP 67580 (ED50:0.19 mg/kg, i.v.), spantide II (ED50:0.33 mg/kg, i.v.), and GR 82334 (ED50:0.26 mg/kg, i.v.), inhibited capsaicin-induced ear oedema, whereas SR 48968 (2.0 mg/kg, i.v.), a NK2 receptor antagonist, had no effect. Furthermore, RP 67580 (0.5 kg/mg, i.v.) inhibited the oedema response induced by reapplication of capsaicin at 50 days after initial treatment. These results indicate that tachyphylaxis of capsaicin-induced oedema is reversible and suggest that this response may be due mainly to a reduction of SP in sensory neurones but not to any loss of responsiveness of NK1 receptors. We also conclude that SP and NK1 receptors are involved predominantly in the development of capsaicin-induced mouse ear oedema.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01837912
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Transport of a gas through asymmetric polysulfone membranes with deposited plasma-polymerized thin layer (1990)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 41 (1990), S. 2427-2436 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A plasma-polymerized thin layer was deposited on the top surface of the skin layer of the asymmetric polysulfone (PSF) membrane to plug ultrafine pores passing through it. Trifluoromethane was used as the monomer gas of plasma polymerization. The steady-state permeation rates for oxygen and nitrogen through the asymmetric PSF membranes with the plasma modification were measured to evaluate the permselectivity and permeability. If ultrafine pores passing through the asymmetric membrane can be plugged by the plasma-polymerized thin layer, the separation factor of oxygen relative to nitrogen can be increased with the permeation rate coefficient of oxygen still kept large. This condition was met when the vaporization time of the cast solution during the preparation of an asymmetric membrane ranged from 10 to 120 s and the plasma polymerization time ranged from 15 to 30 min.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1990.070410942
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Viscosity of concentrated styrene solutions of polystyrene (1968)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 12 (1968), S. 9-11 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Viscosities of concentrated solutions of polystyrene of different intrinsic viscosities were measured at varying polymer concentration and temperature. By modifying Martin's equation, an empirical equation correlating the viscosity of the solution as a function of the polymer concentration, the intrinsic viscosity of the polymer, and temperature was obtained.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1968.070120102
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Polymerization in submonolayers of styrene monomer adsorbed from its vapor phase (1988)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part B: Polymer Physics 26 (1988), S. 1519-1527 
    Details
    ISSN: 0887-6266
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The surface coverage of porous glass (PD = 500 Å) by styrene adsorbed from its vapor (0.1-6 torr) was studied in a vacuum electrobalance. The adsorption isotherm of the monomer was analyzed by the BET method, and a full monolayer coverage was found to form at a relative pressure of 0.11, weighing 6 mg per gram of glass. Polymerization in submonolayers of adsorbed styrene was initiated by thermal decomposition of predeposited BPO and found to continue until all initiator decomposed, sample cooled, or vapor removed, hence allowing a controlled film thickness. The films were extracted in THF and analyzed by computerized GPC. Molecular weights were in the range 18000-69000. These were related to the rates of polymerization by the usual statistical correlations.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/polb.1988.090260713
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    Paper (German National Licenses)
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