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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 54 (1976), S. 899-900 
    ISSN: 1432-1440
    Keywords: Peptisches Geschwür ; Behandlung ; Diät ; Bettruhe ; Arzneimittel ; Peptic Ulcer ; Treatment ; Diet ; Bedrest ; Drugs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary In chronicgastric ulcer bed rest, leaving out smoking and carbenoxolone have increased the rate of healing. In chronicduodenal ulcer it has yet to be shown that anymedical measure so far significantly altered the course of the disease. The surgical approach to the treatment of chronic duodenal ulcer is based upon three principles, all of them aiming at reducing the acid-pepsin secretion: a) Removal of the acid secreting mucosa decreases the acid secretory capacity of the stomach; b) Removal of the pyloric antrum eliminates the main source of gastrin, the major known humoral excitant of acid secretion; c) Section of the vagi probably renders the acid secreting cells less responsive to humoral stimulation (Brooks). The major problem, however, which is theprevention of recurrent duodenal ulcer is yet unsolved. There is some hope that the new receptor blocking agent metiamid is the first step, and there is even more hope in that the proceedings of this symposium will show us further steps forward.
    Notes: Zusammenfassung Die logische Basis für die Behandlung des Geschwürleidens (Ulcus ventriculi oder Ulcus duodeni) liegt in der Grundvorstellung, daß ohne Säure kein Ulcus entsteht und in der Tatsache, daß, wer einmal ein Ulcus hatte, immer Kandidat für ein nächstes Ulcus ist. Unter den internistischen (konservativen) Maßnahmen haben Bettruhe und Karbenoxolon für dasMagengeschwür einen heilungsverkürzenden Einfluß. Alle anderen Maßnahmen wie Diät, Antacida und/oder Cholinergica beeinflussen den Schmerz, aber nicht die Heildauer.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 57 (1995), S. 336-339 
    ISSN: 1432-0827
    Keywords: Total body absorptiometry ; Bone mineral density ; Lean mass ; Fat mass ; Healthy males
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract We examined age-related changes of the entire skeleton and its major anatomical areas (spine, trunk, pelvis, arms, legs) in 139 healthy males (19–99 years of age) and evaluated the influence of lean mass and fat mass on these changes. The population studied was stratified according to their ages referred in decades. Bone mineral density (BMD) and body composition (fat mass, lean mass) were measured by Lunar DPX. A negative linear correlation between BMD values and age was observed. The overall bone loss from the young to the aged was statistically significant for all skeletal sites, with a lower level of significance for the spinal area: BMD percentage decrease ranged from 19.4% for the pelvis to 9% for the spine. Peak bone mass was observed in the first decade (19–29 years of age). Soft tissue increased until the fifth and sixth decades, followed by a gradual decrease. Lean mass declined in a uniform way from the first to the last decades. BMD values were significantly related to lean mass, but there were no correlations with the fat mass. Lean body mass was significantly related to BMD/height, index of “true” volumetric density. Multiple regression analysis confirmed that in males the principal determinant of total body bone density is fat-free mass.
    Type of Medium: Electronic Resource
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