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  • Biogenic amines  (1)
  • Key words: Bone mass — Intestinal calcium absorption — Aging in men.  (1)
  • 1
    ISSN: 1432-0827
    Keywords: Key words: Bone mass — Intestinal calcium absorption — Aging in men.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. Although about 25% of all hip fractures occur in men, little is known about the pattern of their age-related bone loss and its main determinants. The aim of this cross-sectional study was to evaluate the age-related changes of intestinal calcium absorption, bone mass, and bone turnover in normal men. In 70 normal males (age 17–91 years), we measured spinal and forearm bone density (FBD) (by DXA), fractional intestinal calcium absorption (by oral test), serum immunoreactive parathyroid hormone (PTH), dietary calcium intake (diet records), biochemical markers of bone turnover (serum alkaline phosphatase (ALP), osteocalcin, urine calcium, creatinine, and hydroxyproline), and 1,25(OH)2D3 serum levels. Vertebral bone density (VBD) showed a modest decline before age 50 and a greater decline after age 50, whereas FBD presented a significant decrease with advancing age starting at age 40, suggesting a predominant age-related cortical bone loss. Intestinal calcium absorption (47CaFA) and serum 1,25(OH)2D3 also presented an age-related decline similar to FBD. Simple correlation analysis revealed that age was significantly related to 47CaFA (r = 0.60), calcium intake (r = 0.32), VBD and FBD (r = 0.79 and 0.63, respectively), serum 1,25(OH)2D3 (r = 0.69), and serum iPTH (r = 0.72). No significant correlation was found between age and biochemical markers of bone remodeling. Partial correlation and stepwise variable selection analyses, using 47CaFA and bone mass as dependent variables, showed that in normal males, serum 1,25(OH)2D3 and dietary calcium intake were the main contributors (64%) to 47CaFA variability, whereas only age accounted for 63% of VBD and age and dietary calcium accounted for 45% of FBD variability. These results indicate that bone loss in men accelerates after age 50 years and that among other factors, intestinal calcium malabsorption and 1,25(OH)2D3 serum levels play a role.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-143X
    Keywords: Biogenic amines ; biosensors ; fish quality ; K1 value ; sea bass (Dicentrarchus labrax) ; storage conditions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Biosensors in the detection of K1 value (a ratiobased on the changes in ATP catabolites contentoccurring in the muscle after death) and biogenicamines for evaluation of fish quality were tested. TheK1 value was determined, every 24 h, from 24 to168 h after death, by HPLC and by a xanthine oxidasebiosensor on 36 sea bass (Dicentrarchus labrax)stored at 1°C with ice covering. TheK1 value by biosensor and the biogenic amines byHPLC and by a diamine-oxidase biosensor were evaluatedevery 24 h after death or thawing until spoilage on150 sea bass, reared under aeration or atsupersaturated oxygen level and stored at 4°C,1°C with ice covering, −20°C × 30 d and−80°C × 90 d. Refrigerated fish were evaluatedby the EU sensory scheme. A close relation betweenHPLC and biosensor-values emerged for K1 value.Reliable estimates by biosensor K1% of both EUfreshness classes and the quality of frozen bass werefound. Biogenic amine levels remained fairly lowwithin the edibility period but putrescine showed moreevident changes, making it promising as a spoilageindicator in frozen fish. Storage conditions markedlyinfluenced changes after death or thawing in K1value or, even less, in biogenic amine levels,putrescine particularly, while dissolved oxygen inwater of rearing did not.
    Type of Medium: Electronic Resource
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