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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    HNO 45 (1997), S. 385-388 
    ISSN: 1433-0458
    Keywords: Schlüsselwörter Langsame Augenfolgebewegungen ; Blickfolgeprüfung ; Glatte Blickfolge ; Zentral-vestibuläre Störung ; Pendelblickfolgetest ; Key words Central vestibular disease ; Smooth pursuit eye movements ; Pendular eye-tracking test
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Testing gaze movements is very important for the detection of central vestibular diseases. The intent of this study was to clarify the pathological importance of partially disturbed and completely disturbed smooth pursuit movements. One hundred patients were analyzed and curves of smooth pursuit movements were classified into three groups of different deformations: i.e, regular, partially disturbed and completely disturbed movements. The correlation index of each curve was then calculated. In 16 patients qualitative analysis showed a completely disturbed result in the smooth pursuit test. Nine of the patients (56.3%) showed morphological signs of a central disease. Twenty-nine patients yielded a partially disturbed test result and in 2 of them (6.9%) a central pathological illness was uncovered. Patients with completely disturbed smooth pursuits showed the highest average binocular correlation index (1.44). Others with partially disturbed results gave an index of 1.24, while persons with regular smooth pursuits yielded a value of 1.17. Because of the scattering seen, it was not definitely possible to attach a correlation index to central disease. On the other hand, an index higher than 1.3 should arouse suspicion for a central illness. Only completely disturbed smooth pursuit movements frequently appear in connection with central diseases. As a rule, a partially disturbed result does not indicate diseases of the central nervous system.
    Notes: Zusammenfassung Die Prüfung der willkürlichen langsamen Augenfolgebewegungen liefert wichtige Hinweise zur Aufdeckung zentral vestibulärer Störungen. Ziel war es zu klären, ob neben der komplett gestörten auch einer partiell gestörten Blickfolgebewegung ein Krankheitswert zukommt. Retrospektiv wurde bei 100 Patienten die Blickfolgeprüfung analysiert. Die einzelnen Kurvenverläufe wurden den 3 Gruppen der regelrechten, der partiell gestörten und der komplett gestörten Blickfolge zugeordnet und anschließend der Übereinstimmungsquotient errechnet; 16 Patienten zeigten qualitativ eine komplett gestörte Blickfolge, und bei 9 von ihnen (56, 3%) ließ sich ein morphologisches Korrelat im Sinne einer zentralen Erkrankung finden. Bei 29 Patienten ergab sich eine partiell gestörte Blickfolge, und nur bei 2 von ihnen (6,9%) fand sich eine zentrale Pathologie. Durchschnittlich fand sich der höchste beidäugig gemessene Übereinstimmungsquotient mit 1,44 in der Gruppe mit komplett gestörter Blickfolge. In der Gruppe mit partiell gestörten Augefolgebewegungen lag er bei 1,24 und in der mit regelrechter Blickfolge bei 1,17. Nur eine komplett gestörte Blickfolge korreliert in den meisten Fällen mit einer zentralen Erkrankung. Partiell gestörte Augenfolgebewegungen haben in der Regel keine pathologische Bedeutung.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 109 (1925), S. 41-58 
    ISSN: 0021-8383
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 20 (1937), S. 1059-1077 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 1. Azoprotein (sowohl in vitro hergestelltes als in vivo entstehendes) enthält entsprechend der Annahme von Pauly die Azo-gruppierung —N=N—.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 34 (1951), S. 1937-1943 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird die Synthese von Derivaten des 1,2-Diaminocyclohexans und deren Antihistaminwirksamkeit beschrieben.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 35 (1952), S. 2556-2560 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird die Dienkondensation von Butadien und Alkylidencyanessigestern zu alkylierten 1-Cyano-Δ4-cyclohexencarbonsäureestern, die Hydrierung zu den entsprechenden Cyclohexanderivaten und die Überführung der letzteren in cyclische Derivate des Malonamidesters beschrieben.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 42 (1959), S. 1572-1581 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: One known and four new alkaloids have been isolated from C. durissima STAPF. Isovoacangine (VII) (first isolated from Stemmadenia), conopharyngine (VIII), and possibly also Alkaloid E are monomeric isoquinuclidine bases found in root and stem bark; conodurine and conoduramine, however, are dimeric and found only in the roots. A mild and simple method is described for the decarbomethoxylation of ester bases of the voacangine type to substances of the ibogaine type.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 35 (1952), S. 2561-2569 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 1Es wird die Kondensation von 1,4-Dihalogenalkanen und Cyanessigester zu alkylsubstituierten 1-Cyano-cyclopentancarbonsäureestern und die Verseifung der letzteren zu alkylierten 1-Carbamylcyclopentancarbonsäureestern beschrieben.2Pharmakologisch zeigen der racemische und der meso-1-Carbamyl-2,5-dimethyl-cyclopentancarbonsäure-äthylester in bezug auf ihre narkotischen Eigenschaften und Ihre Toxizität einen deutlichen Unterschied.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 42 (1959), S. 878-886 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 4-Hydroxycoumarin reacts with substituted salicylaldehydes, 2,6-dichloro- or -chloro-nitro-benzaldehydes to yield unstable 3,3′-benzylidene-bis-(4-hydroxycoumarins), intermediates which undergo ring closure with the hydroxyl group of one of the 4-hydroxycoumarin moieties, producing derivatives of 7-[4′-hydroxycoumarinyl-(3′)]-benzopyrano [ 3,2-c] coumarins.2,6-Dimethylbenzaldehyde, pyridine-2-aldehyde and 6-methylpyridine-2-aldehyde undergo a similar reaction.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 42 (1959), S. 887-889 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Preparation and properties of the stereoisomeric 2-dimethylamino-cyclohexanyl acetates and benzilates are described. The analogous mandelates cannot be prepared through the corresponding 2-chloro-2-phenylacetates because cis Z-dimethylamino-cyclohexanol reacts with 2-chloro-2-phenylacetyl chloride to form the quaternary chloride VIII, and trans 2-dimethylamino-cyclohexanyl 2-chloro-2-phenylacetate, with water, suffers saponification prior to substitution.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 33 (1950), S. 1208-1217 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird die Synthese von Diaryl-alkenylaminen beschrieben. Auf Grund der Darstellungsmethode, des Hydrierungsverlaufes und der oxydativen Abbaureaktion wird den neuen Verbindungen die Konstitution von α-(Aminoalkyl)-stilbenen gegeben.
    Additional Material: 4 Tab.
    Type of Medium: Electronic Resource
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