ISSN:
0935-6304
Keywords:
Block polysiloxanes
;
Functionalized polysiloxanes
;
Chiral polysiloxanes
;
Enantioselective stationary GC phase
;
Polysiloxane synthesis
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Trifluoroethyl ester-functionalized polysiloxanes can be prepared by block condensation of 3-dichloromethylsilyl-2-methylpropionic acid 2′,2′,2′-trifluoroethyl ester with 1,5-bis(diethylamino)hexamethyltrisiloxane or with disodium tetramethyldisiloxane-1,3-diolate. The functionalized polysiloxanes may serve as supports for a variety of selector groups; for instance, nucleophilic displacements with L-valine-t-butylamide or L-α-naphthylethylamine lead to chiral polysiloxanes in high yields and with high reproducibility. Imidazole accelerates the rate of nucleophilic displacement. Capillary columns coated with such chiral polysiloxanes exhibit high enantioselectivity and thermostability.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jhrc.1240170103
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