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  • Blood specimen collection  (2)
  • Facultative thermophile  (2)
  • Polymer and Materials Science  (2)
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Keywords
  • 1
    Electronic Resource
    Electronic Resource
    The orbital venous plexus as a sampling site for coagulation testing: The continuing saga (1994)
    Springer
    Comparative clinical pathology 4 (1994), S. 236-238 
    Details
    ISSN: 1433-2981
    Keywords: Blood coagulation ; Blood specimen collection ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Papers have recently been published regarding the acceptability of samples obtained from the orbital venous plexus for coagulation testing (Dameron et al. 1992; Edwards and Fuller 1993; Matsuzawa et al. 1994; Salemink et al. 1994). Meetings of the committee for International Harmonisation for Clinical Pathology Testing (IHCPT) have highlighted the concerns of sampling from the orbital venous plexus (OVP), both ethical considerations and validity of data. In response to a letter to the editor (Weingand, 1994) and to enable informed and objective discussion of this topic, this paper presents coagulation data on samples obtained from the OVP, collected by several pharmaceutical companies using a variety of systems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00185180
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of bleeding site on coagulation results in the Charles river outbred albino SD rat (1992)
    Springer
    Comparative clinical pathology 3 (1992), S. 40-42 
    Details
    ISSN: 1433-2981
    Keywords: Blood coagulation ; Blood specimen collection ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The UK Home Office currently advises that the amount of blood to be taken during a toxicology study is limited to 15% of an animal's blood volume (equivalent to approximately 1 ml per 100 g of the animal's bodyweight) in a 28 day period. At SmithKline Beecham, blood samples for routine haemtology and clinical chemistry analyses during a study have been obtained from the orbital sinus (OS). Adequate samples can be obtained for all routine assays with the exception of coagulation tests, and the possibility has been investigated of taking terminal coagulation samples from the posterior vena cava (PVC) as part of the post-mortem procedures, and compared the prothrombin (PT) and activated partial thromboplastin (APTT) times obtained on blood samples from each source. There was no biologically significant difference between samples taken from OS and PVC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00394926
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Production of a thermostable ATPase by the facultative thermophile, Bacillus coagulans (1983)
    Springer
    Archives of microbiology 135 (1983), S. 74-76 
    Details
    ISSN: 1432-072X
    Keywords: ATPase ; Bacillus coagulans ; Facultative thermophile ; Thermoadaptation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The properties of the ATPase in the facultative thermophile, Bacillus coagulans, grown at thermophilic or mesophilic temperatures were similar. Arrhenius plots did not show discontinuities indicative of thermoadaptation. Magnesium stimulation of the enzyme was dependant on the assay temperature but independant of the growth temperature. The ATPase in cells grown at 35°C or 55°C was equally thermostable at 65°C. In contrast, the ATPase from the mesophile, Bacillus megaterium (T max=42°C) was completely inactivated at 55°C in 5 min.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00419486
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    The respiratory chain of the facultative thermophile, Bacillus coagulans (1986)
    Springer
    Archives of microbiology 145 (1986), S. 347-352 
    Details
    ISSN: 1432-072X
    Keywords: Bacillus coagulans ; Facultative thermophile ; Respiratory chain ; Inhibitors ; Cytochromes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Two oxidases were found to be present in membranes from the facultative thermophile Bacillus coagulans grown at 55°C, compared to one in cells grown at 37°C. Cytochrome spectra and inhibitors of the respiratory chain identified them as cytochrome oxidases aa 3 and d. Both were present in membranes from 55°C grown cells, but only cytochrome oxidase aa 3 was found in membranes from 37°C grown cells. The presence of cytochrome d in 55°C grown cultures was found to be due to decreased oxygen tension and not to the high growth temperature. This was confirmed by (a) induction of cytochrome d at 37°C under conditions of oxygen limitation and (b) its repression at 55°C under conditions of high aeration and its subsequent induction on lowering the dissolved oxygen concentration in chemostat cultures. Two cytochromes b (λmax 558 and λmax 562) were present in both 37°C and 55°C grown cells. Results from the inhibition of substrate oxidation by membranes suggested different pathways of electron transport by the respiratory chain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00470869
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Crystallization-gelation process of homopolymers and copolymers from solution (1982)
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Letters Edition 20 (1982), S. 355-359 
    Details
    ISSN: 0360-6384
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pol.1982.130200701
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Wide-angle neutron scattering studies of mixed crystals of polyethylene and deuteropolyethyleneResearch sponsored by the Division of Materials Sciences, U.S. Department of Energy, under contract W-7405-eng-26 with the Union Carbide Corporation and National Science Foundation under Grant No. DMR-7621925. (1982)
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Physics Edition 20 (1982), S. 245-258 
    Details
    ISSN: 0098-1273
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Wide-angle neutron scattering studies have been made of a series of mixed crystal blends of polyethylene and deuterated polyethylene in the range 0.68 ≤ K = 4πλ-1 sinθ ≤ 2.02 Å-1. Recent calculations by Stamm have shown that regularly folded subunits of small numbers (two to ten) of stems should produce an observable modulation of the diffuse scattering pattern of such mixtures in this K range. For both melt- and solution-crystallized blends, no extra signal was observed above the background scattering level. The data are used to place an upper limit (of about four) on the number of stems that could be regularly folded in the (100) and (010) planes for these materials.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pol.1982.180200207
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    Paper (German National Licenses)
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