Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Effects of Clodronate on Cortical and Trabecular Bone in Ovariectomized Rats on a Low Calcium Diet (1997)
    Springer
    Calcified tissue international 61 (1997), S. 158 -164 
    Details
    ISSN: 1432-0827
    Keywords: Key words: Ovariectomy — Low calcium diet — Clodronate — Bone volume — Bone strength.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. The aim of this study was to evaluate the contribution of a low calcium diet to the cortical and trabecular osteoporosis seen in ovariectomized rats after 7 weeks on a low calcium diet and to investigate the effects of the bisphosphonate clodronate on this development of osteoporosis. Thirty-six mature, female Wistar rats were randomized into four groups: Ovx−B (bisphosphonate) and Ovx−C (control) were ovariectomized, and Sham−Ca (low calcium) and Sham+Ca (normal calcium) were sham operated. The first three groups were fed a low calcium diet (0.01%) and Sham+Ca normal rat chow (Ca 1.1%). The Ovx−B received 10 mg/kg s.c. clodronate daily for nine weeks, and Ovx−C, Sham−Ca, and Sham+Ca received the same volumes of saline. Bone mineral turnover measured as 85Sr-uptake was increased in all low calcium groups compared to Sham+Ca. The Sham+Ca femora had higher dry weight and ash weight than the other groups, and Ovx−C had higher dry weight compared with Ovx−B and Sham−Ca. Calcium content was lower in both Ovx groups compared to both Sham groups. Magnesium was lower in all groups compared to Sham+Ca and higher in Ovx−B compared with Ovx−C. In the femoral shaft, Sham+Ca had significantly higher ultimate bending moment, energy absorption, and deflection compared to the other three groups. Ultimate bending moment was higher in Sham−Ca than in Ovx−C. Stiffness was increased in both Sham+Ca and Ovx−B compared to Ovx−C. The maximum stress in the femoral midshaft was higher in Sham+Ca than in the other groups, and higher in Ovx−B than in Ovx−C. Histomorphometry showed increased medullary area in all low calcium groups compared to Sham+Ca and larger cortical area in Sham+Ca and Ovx−B compared to Ovx−C. Compared to Sham+Ca the trabecular bone volume was decreased to 30% in Sham−Ca and to 9% in Ovx−C, but was unchanged in Ovx−B. The low calcium diet generally increased bone mineral turnover and reduced the tibial bone volume. Femoral changes led to a reduction of cortical fracture strength and maximal stress. Ovariectomy in addition to a low calcium diet reduced femoral strength even more. Daily injections of clodronate to ovariectomized rats on a low calcium diet increased femoral shaft stiffness and maximum stress, and clodronate preserved both trabecular and cortical tibial bone volume completely.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002239900315
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Earlier wrist fracture: A confounding factor in distal forearm bone screening (1992)
    Springer
    Osteoporosis international 2 (1992), S. 201-204 
    Details
    ISSN: 1433-2965
    Keywords: Bone ; Distal radius ; Fracture ; Single photon absorptiometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Thirty-six women aged 60, 70 or 80 years who had fractured one of their distal radii (Colles' fracture) 0 to 35 (median 10) years earlier were examined in this population-based study. Single photon measurements (SPA) were performed on both arms 1 cm and 6 cm proximal to the styloid process of the ulna. All women were questioned about earlier wrist fractures and which, if any, side had been affected. Information about the type and site of the fracture was also gathered from the hospital records. The bone mineral content (BMC) was found to be increased by almost 20% in the once-fractured radius at the distal measuring site (1 cm) when compared with the unaffected side. This difference did not seem to diminish with time. At the proximal measuring site there was no difference between the once-fractured and the non-fractured side. There was a progressive loss of bone mineral in the once-fractured arm during the first years after the fracture however. This appeared to be reversed after about 10 years to a relative gain, even though the correlation was weak. Six of the 36 women could not remember which side had been fractured and five could not remember having had such a fracture at all. Determination of osteoporosis by measuring forearm BMC with single photon densitometry is therefore of limited value in some women of the oldest age groups.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01623927
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Is bone mineral density advantage maintained long-term in previous weight lifters? (1995)
    Springer
    Calcified tissue international 57 (1995), S. 325-328 
    Details
    ISSN: 1432-0827
    Keywords: Bone mineral density ; Bone mass measurements ; Duarenergy X-ray absorptiometry ; Weight lifting ; physical activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract This cross-sectional study was done in order to ascertain whether there is a lifelong beneficial effect on bone mineral density (BMD) of early, long-lasting, and intense physical exercise. Forty-eight male ex-weight lifters, mean age 64 years (range 50–79) participated. They had followed a training program of an average of 10 hours/week (range 4–20) for an average of 13 years (range 1–34). They had all retired from competitive sport an average of 30 years (range 7–50) ago. Sixty-six age-matched volunteers served as controls. The bone mineral density (BMD, areal density, g/cm2) in the total body, spine, and hips and the fat content and lean body mass were measured with the LUNAR DPX bone mass scanner. In ex-weight lifters 50–64 years of age, the BMD was greater than in controls. After 65 years, no difference was found between the former weight lifters and their controls.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00302066
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Post-traumatic osteoarthrosis after tibial shaft fractures A 30-year-follow-up (1993)
    Springer
    European journal of orthopaedic surgery & traumatology 3 (1993), S. 255-256 
    Details
    ISSN: 1432-1068
    Keywords: Fracture tibiale ; Diaphyseal ; Posttraumatic osteoarthrose ; Tibial fracture ; Diaphyseal ; Posttraumatic osteoarthrosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary In 1990, a retrospective case control study was performed based on all patients with tibial shaft fractures (n = 767) treated at the Department of Orthopaedics in Malmö 1949–1963. At the time of the study 231 of the patients were still living in Malmö . All radiographic examinations of this latter group from the time of the fracture to 1990 were studied and the occurrence of osteoarthrosis (OA) of the hip, knee and ankle joints were registered. The fracture patients were compared with an age and sex-matched control group. The group with previous tibial shaft fracture had an increased prevalence of OA in the lower extremities compared with the controls. When comparing the risk of OA in the once fractured limb with the uninjured side we found no difference. We conclude that there is no risk of having posttraumatic OA after extra-articular tibial shaft fractures.
    Notes: Résumé En 1990, une étude de contrôle est réalisée en se référant à tous les patients ayant eu des fractures de la diaphyse tibiale (n = 767) traitées dans le Département d'Orthopédie de Malmö entre 1949 et 1963. Lors de ce contrôle 231 patients vivaient toujours à Malmö. Tous les examens radiographiques de ce dernier groupe, à partir du moment de la fracture jusqu'à 1990 ont été étudiés et on a noté tous les cas de survenue d'arthrose de la hanche, du genou et de l'articulation de la cheville. Ces cas de fractures tibiales sont comparées à un groupe de contrôle de même âge et de même sexe. Le groupe des patients avec antécédent de fracture de la diaphyse tibiale présente une prédominance d'arthrose dans les membres inférieurs en comparaison avec les témoins. Nous n'avons relevé par contre aucune différence significative en comparant le risque d'arthrose dans le membre fracturé avec celui du côté intact. Nous concluons donc qu'il n'y a aucun risque d'avoir une arthrose post-traumatique après une fracture diaphysaire tibiale.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01796530
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...