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  • 1
    ISSN: 1569-8041
    Keywords: CD30L ; CD40L ; FasL ; Hodgkin's disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Reed–Sternberg cells of Hodgkin's disease express CD30and CD40 receptors. The ligands for these receptors have been reported tohave pleiotropic biologic activities in vitro, including induction of celldeath. Expression of the ligands for these receptors in lymph nodes involvedwith Hodgkin's disease is not known. Purpose: The purpose of this study was to examine CD30 ligand (L) andCD40L expression in lymph nodes of patients with Hodgkin's disease, and tostudy CD30L expression on nodal lymphocyte subsets. Materials and methods: CD30L expression on subsets of lymphocytes of fivelymph nodes involved with Hodgkin's disease was determined by two-colorFACScan. Messenger RNA expression of CD30L and CD40L was determined by thereverse-transcriptase polymerase chain reaction (RT-PCR) method performed onseven specimens involved with Hodgkin's disease (five lymph nodes and twospleens). Results: Four of seven specimens (57%) contained cells thatexpressed CD30L mRNA and three specimens (43%) containedCD40L-expressing cells. The mean percentage of nodal lymphocytes expressingCD30L surface protein was ≤20%. Conclusion: Hodgkin's disease lymph nodes and spleens frequently lackCD30L- and CD40L-expressing cells, and when CD30L is expressed, it is usuallydetected on few numbers of lymphocytes. The differences in the level ofexpression of these ligands in Hodgkin's disease lymph nodes may be relatedto the disease's clinical behavior.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1569-8041
    Keywords: CD30L ; CD40L ; FasL ; Hodgkin's disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Reed–Sternberg cells of Hodgkin's disease express CD30and CD40 receptors. The ligands for these receptors have been reported to have pleiotropic biologic activities in vitro, including induction of cell death. Expression of the ligands for these receptors in lymph nodes involved with Hodgkin's disease is not known. Purpose: The purpose of this study was to examine CD30 ligand (L) andCD40L expression in lymph nodes of patients with Hodgkin's disease, and to study CD30L expression on nodal lymphocyte subsets. Materials and methods: CD30L expression on subsets of lymphocytes of five lymph nodes involved with Hodgkin's disease was determined by two-color FACScan. Messenger RNA expression of CD30L and CD40L was determined by there verse-transcriptase polymerase chain reaction (RT-PCR) method performed on seven specimens involved with Hodgkin's disease (five lymph nodes and two spleens). Results: Four of seven specimens (57%) contained cells that expressed CD30L mRNA and three specimens (43%) containedCD40L-expressing cells. The mean percentage of nodal lymphocytes expressingCD30L surface protein was ≤20%. Conclusion: Hodgkin's disease lymph nodes and spleens frequently lackCD30L- and CD40L-expressing cells, and when CD30L is expressed, it is usually detected on few numbers of lymphocytes. The differences in the level of expression of these ligands in Hodgkin's disease lymph nodes may be related to the disease's clinical behavior.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 41 (1998), S. 1321-1337 
    ISSN: 0029-5981
    Keywords: distributed parallelization ; finite elements ; coarse-grain parallelism ; Engineering ; Numerical Methods and Modeling
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Parallel simulation of incompressible fluid flows is considered on networks of homogeneous workstations. Coarse-grain parallelization of a Taylor-Galerkin/pressure-correction finite element algorithm are discussed, taking into account network communication costs. The main issues include the parallelization of system assembly, and iterative and direct solvers, that are of common interest to finite element and general numerical computation. The parallelization strategies are implemented on a Sun workstation cluster using the Parallel Virtual Machine (PVM) message passing library. Test results are obtained with a maximum of nineteen workstations and various PVM configurations are exhibited. Parallel efficiency close to ideal has been achieved for some strategies adopted. It is suggested that load balancing may not always be beneficial on distributed platforms with broadcasting communication connection. © 1998 John Wiley & Sons, Ltd.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 11 (1987), S. 33-50 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: The upper bound method of limit analysis of perfect plasticity is applied to stability problems of slopes with a general nonlinear failure criterion. Based on the upper bound method, a numerical procedure is suggested, which converts the complex system of differential equations to an initial value problem. Using this numerical procedure, an effective numerical method, called the inverse method, suitable for the solution of slope stability problems in soil mechanics with a general nonlinear failure criterion, is presented. A general nonlinear failure criterion for soils is also suggested, from which the effects of nonlinear failure parameters on the stability of slopes are discussed.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
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