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  • Calcium  (2)
  • Polymer and Materials Science  (2)
  • Primary structure  (2)
  • 1
    ISSN: 0014-5793
    Keywords: Aorta ; Cyclic nucleotidegated channel ; Expression ; Primary structure
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0014-5793
    Keywords: Ca^2^+ channel ; Expression ; Primary structure ; Smooth muscle
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 353 (1995), S. 1-10 
    ISSN: 1432-1912
    Keywords: Key words Cyclic nucleotide-gated channels ; Second messenger ; Cyclic GMP ; Calcium ; Nitric oxide ; Molecular cloning ; Gene family
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Cyclic nucleotide-gated cation channels (CNG channels) form a multi-gene family consisting of at least five distinct members (CNG1–5). Expression studies have indicated that only CNG1–3 are able to form functional homooligomeric channels. Although structurally related, the cDNAs of CNG4–5 fail to induce cyclic nucleotide-dependent currents when expressed alone. However, when co-expressed with CNG1–3 they confer some of the physiologically observed properties of native CNG channels which are absent from the homooligomeric CNG1–3 channels. CNG channels are expressed in several tissues and cell types pointing to a general function of these channels in a wide variety of cellular systems. There is now increasing evidence that a major function of CNG channels may consist in providing a second messenger-regulated pathway for Ca2+ influx.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-2013
    Keywords: Skinned coronary arteries ; Smooth muscle ; Regulation of contractile tone ; cAMP-dependent protein kinase ; cAMP-dependent modulation of contractile tone ; Calmodulin ; Calcium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Maximally contracted detergent skinned coronary smooth muscle fibres are relaxed by lowering the concentration of free Ca2+. The extent and rate of relaxation depends on the concentration of free Ca2+ and calmodulin (CaM) suggesting that it is the Ca2+. CaM complex which is responsible for maintaining tension. At a fixed concentration of Ca2+ and CaM further relaxation can be achieved by addition of the catalytic subunit of the cAMP-dependent protein kinase (cAMP-kinase). The extent as well as the relaxation rate depend on the concentration of cAMP-kinase (0.01–0.5 μM) and both are antagonized by high concentrations of Ca2+ and CaM. The Ca2+-requirement for obtaining half maximal concentration is shifted from 1.1 μM to 6.3 μM Ca2+ in the presence of 0.5 μM cAMP-kinase. These data indicate that the response of the contractile apparatus to a change in the free [Ca2+] can be modulated by cAMP-kinase at the level of the contractile proteins. It is further suggested that the tone of coronary smooth muscle is determined by the relative and not by the absolute concentrations of Ca2+, CaM and cAMP-kinase.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 29 (1998), S. 281-291 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Investigation of Laser Beam Joining Properties for Eye Glass Frame ManufactureIn the production of high-grade eye glass frames of stainless steel increase the application of laserbeam joining technology in comparison to conventional processes. In a study it should be established, with which process (brazing or welding), the practical requirements of eye glass frames could be realized. Profiles made of Cr-Ni-steel which are used in practice due to their corrosion resistance, were joined with laser beam. To characterize the properties of joints, the quality of specimens were tested concerning mechanical properties (hardness, strength, ductility) and structural constitution. In relation to the requirement of good ductility of the joints, it was possible to proof the advantages of the welded samples.
    Notes: Bei der Fertigung von hochwertigen Brillengestellen aus nichtrostenden Stählen gewinnt der Einsatz der Laserstrahlfügeverfahren im Vergleich zu konventionellen Verfahren zunehmend an Bedeutung. Im Rahmen einer Studie sollte festgestellt werden, welches der beiden Verfahren Löten und Schweißen die in der Praxis gestellten Anforderungen an Brillengestelle besser erfüllt. Hierzu wurden Profile aus Cr-Ni-Stahl, wie sie in der Praxis wegen ihrer besonderen Langzeitstabilität gegenüber Korrosion eingesetzt werden, mittels Laserstrahl gefügt. Zur Charakterisierung der metallurgischen Eigenschaften der Fügeverbindungen wurden die Qualitätsmerkmale der Proben hinsichtlich mechanischer Eigenschaften (Härte, Festigkeit und Verformbarkeit) sowie die Gefügeausbildung untersucht. Im Hinblick auf die geforderte gute Verformbarkeit der Verbindungen konnte für die geschweißten Proben ein Vorteil gegenüber dem Laserstrahllöten nachgewiesen werden.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 48 (1976), S. 993-999 
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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