ISSN:
1432-2013
Keywords:
Carotid Body
;
Chemoreceptor Activity
;
Tissue $$P_{O_2 }$$
;
Local Blood Flow
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The relationship between $$P_{GO_2 }$$ , $$P_{aO_2 }$$ , local blood flow, and the activity of individual chemoreceptor fiber units of the cat's carotid body was studied during changes in the arterial oxygen partial pressure and the arterial systemic blood pressure. The following results were obtained: 1. In the normal physiological range $$P_{GO_2 }$$ follows $$P_{aO_2 }$$ almost linearly. 2. The curves of neuronal activity depending on $$P_{aO_2 }$$ or $$P_{GO_2 }$$ have different shapes. 3. Hypoxia and hyperoxia change the relationship between $$P_{aO_2 }$$ and $$P_{GO_2 }$$ as well as the relationship to the neuronal activity. When returning to normal conditions, the initial relationship is re-established. 4. Considerable changes in local flow do not change local tissue $$P_{O_2 }$$ and do not influence the neuronal activity.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00595816
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