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  • 1
    ISSN: 1126-5442
    Keywords: Key words Carbon monoxide poisoning ; Delayed neurologic sequelae ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The clinical and neuroradiological outcome of carbon monoxide (CO) intoxication was evaluated prospectively in 30 patients over a follow-up period of 3 years. Among the patients studied, 22 had been acutely exposed to CO while 8 were chronically exposed. One month after CO poisoning, 12 of the 22 patients with acute intoxication showed magnetic resonance imaging (MRI) abnormalities: 6 also had neurological sequelae and 6 were asymptomatic. The remaining 10 patients showed neither MRI abnormalities nor neurological sequelae. During the 3-year follow-up, 4 of the patients with both MRI abnormalities and neurological sequelae improved in both clinical features and MRI findings. One of the 6 asymptomatic patients with MRI abnormalities developed a progressive cognitive impairment 2 months after acute intoxication, with a concomitant severe worsening of the MRI lesions. Among the 10 patients with neither MRI abnormalities nor neurological sequelae, only 1 developed neurological sequelae after a clear period of 4 months. In the group of patients who experienced chronic CO intoxication, only 1 presented with a neuropsychiatric syndrome which improved at follow-up. Brain MRI showed white matter lesions which remained unchanged at control scan after 1 year. In conclusion, we observed that some patients with severe CO poisoning and neurological sequelae may fully regain normal functions after approximately 1 year. The presence of MRI lesions 1 month after CO poisoning did not accurately predict the subsequent outcome. The observation of a clear period longer than the usual 2–40 day interval in 2 patients should be considered for careful planning of follow-up and for prognosis in CO-poisoned patients.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1590-3478
    Keywords: Carotid occlusion ; spontaneous carotid dissection ; nonatherosclerotic carotid disorder ; spontaneous carotid recanalization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Abbiamo studiato 7 pazienti con occlusione dell'arteria carotide interna conseguente a dissezione arteriosa spontanea. Tutti i pazienti avevano presentato stroke, in uno associato con sindrome di Horner. L'esame dopplersonografico mostrava occlusione carotidea, ma solo lo studio angiografico permetteva di definire la diagnosi di questa patologia vascolare non aterosclerotica. Si osserva ricanalizzazione spontanea della carotide interna al controllo angiografico dopo 6–9 settimane in 6 casi, trattati solo con farmaci antiaggreganti. Solo in un pazienti i controlli seriati con doppler transcranico confermavano la persistenza dell'occlusione a distanza di sei mesi.
    Notes: Abstract We studied 7 patients with internal carotid occlusion following spontaneous arterial dissection. All presented strokes, in one associated with Horner's syndrome. The doppler examination showed carotid occlusion, but only angiography established the diagnosis of vascular disease. Spontaneous recanalization was observed in 6 cases, treated only by antiplatelet drugs.
    Type of Medium: Electronic Resource
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