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  • Cartilage degeneration  (1)
  • Coronary complication  (1)
  • Fertilization  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Antibodies to native type III collagen in the serum of patients with Kawasaki disease (1992)
    Springer
    European journal of pediatrics 151 (1992), S. 183-187 
    Details
    ISSN: 1432-1076
    Keywords: Kawasaki disease ; Coronary complication ; Antibody to type III collagen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pathological studies have revealed that the vasculitis in Kawasaki disease (KD) begins in the intima and the adventitia of blood vessels resulting in panvasculitis. In the present study we investigated the possibility that auto-antibodies to types III and II collagen are involved in the vascular injury. Seven out of 38 patients (18%) with KD had elevated serum levels of IgG anti-body to type III collagen. None had increased serum antibodies to type II collagen. Specificity of the antibody to type III collagen in patients with KD was 86%. Three out of seven KD patients (42.9%) with coronary complications had elevated serum levels of the antibody. It is conceivable that the more severe the inflammation of systemic blood vessels, the more frequently antibodies to type III collagen are detected and coronary complications develop. Accordingly, this antibody may be secondarily detected in the serum of KD when systemic blood vessels are severely damaged. Detection of antibodies to type III collagen might be a risk factor predicting coronary complications.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01954380
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Histological comparison of patellar cartilage degeneration between chondromalacia in youth and osteoarthritis in aging (1995)
    Springer
    Knee surgery, sports traumatology, arthroscopy 3 (1995), S. 167-172 
    Details
    ISSN: 1433-7347
    Keywords: Cartilage degeneration ; Chondromalacia patellae ; Osteoarthritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Sports Science
    Notes: Abstract The histological findings of the patellar cartilage were compared between cases of chondromalacia, which occurs predominantly in young persons (22 patients, average age 19.8 years) and cases of osteoarthritis, which is common among the elderly (21 patients, average age 65.4 years). The histological findings of cartilage in the chondromalacia were characterized by increased density and vigorous fibrous metaplasia of chondrocytes. These findings may be considered to represent a reactive change in the chondrocyte. Cartilage degeneration in osteoarthritis, by contrast, is regressive and presents a clearly different histological picture from that of chondromalacia patellae. We conclude that chondromalacia does not easily lead to osteoarthritis. On the other hand, the cartilage was characteristically softened, as observed by gross inspection, and showed rarefaction of the cartilage matrix. It should be noted that the change was not observed in aging, but showed a pattern of cartilage degeneration peculiar to young patients with chondromalacia patellae.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01565477
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Ultrastructural studies on early events in fertilization of the bivalveLaternula limicola (1979)
    Springer
    Protoplasma 100 (1979), S. 73-83 
    Details
    ISSN: 1615-6102
    Keywords: Bivalve ; Fertilization ; Laternula limicola ; Sperm-egg interaction ; Temporary-acrosome ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Ultrastructural studies on sperm-egg interaction at the time of fertilization inLaternula limicola were performed. The “temporary-acrosome” did not change morphologically while the sperm passed through the egg investments. At the onset of sperm entrance into the egg, however, the temporary-acrosome and mitochondria were eliminated from the sperm. Afterwards the sperm was engulfed by the egg surface without membrane fusion of the gametes. After entry the sperm nucleus was surrounded by four membranes: the plasma membranes of the egg and of the sperm, and the membranes of the sperm nuclear envelope. As the sperm nucleus differentiated into the male pronucleus, the plasma membranes of both the sperm and egg were initially vesiculated, then dispersed into the egg cytoplasm. Finally, the sperm nuclear envelope changed into the male pronuclear membrane accompanying sperm chromatin dispersion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01276302
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    Paper (German National Licenses)
    Fulltext
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