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  • 1
    ISSN: 1572-8595
    Keywords: Radiofrequency Energy ; PSVT ; Catheter Ablation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Temperature monitoring may be helpful for ablation of accessory pathways, however its role in ablation of atrioventricular nodal reentrant tachycardia (AVNRT) using the slow pathway approach is unclear. Therefore, the purpose of this study was to prospectively compare slow pathway ablation for AVNRT using fixed power or temperature monitoring. The study included 120 patients undergoing ablation for AVNRT. Patients were randomly assigned to receive either fixed power at 32 watts, or to temperature monitoring with a target temperature of 60°C. The primary success rate was 72% in the fixed power group and 95% in the temperature monitoring group (p=0.001). The ablation procedure duration (35±29 min vs 35±30 min; p=0.9), fluoroscopic time (32±17 vs 35±19 min; p=0.4), mean number of applications (10.2±8.1 vs 8.4±7.9; p=0.2), and coagulum formation per application (0.2% vs 0.5%; p=0.6) were statistically similar in the fixed power and temperature monitoring groups, respectively. The mean temperature (47.3±4.8°C vs 48.6±3.8°C; p〈0.01), and the temperature associated with junctional ectopy (48.2±3.8°C vs 49.3±3.6°C, p〈0.01) were less for the fixed power than the temperature monitoring group. In the temperature monitoring group, only 31% of applications achieved an electrode temperature of 60°C. During follow up of 6.6±3.6 months there were two recurrences in the fixed power group and one in the temperature monitoring group (p=1.0). In summary, power titration directed by temperature monitoring was associated with an improved primary procedural success rate. Applications of energy were associated with a temperature of approximately 50°C with both techniques, suggesting that there is a low efficiency of heating in the posterior septum.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 41 (1981), S. 115-120 
    ISSN: 1432-1106
    Keywords: Imprinting ; Synapse ; Hemispheric asymmetry ; Domestic chicks
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fourteen chicks were hatched and reared in darkness to ≅ 21 h when they were exposed to overhead illumination for 0.5 h and then to an imprinting stimulus (a pulsing red light) for 20 min. The chicks were then matched in pairs on the basis of their activity. One member of each pair was returned to the dark and the other was trained for a further 120 min. All chicks were killed ≅ 6.5 h after the onset of training and perfused with fixative. Blocks were removed bilaterally from a restricted part of the hyperstriatum ventrale and prepared for electronmicroscopy. Various synaptic features were measured, all counts being performed ‘blind’. In undertrained chicks the length of the synaptic apposition zone in this part of the left hemisphere was shorter than that in the right by a mean value of 35±11.4 (SEM) nm. Further training eliminated this difference. No other synaptic measurements were affected by prolonging the period of training.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 41 (1981), S. 121-123 
    ISSN: 1432-1106
    Keywords: Cholinergic receptors ; Chick brain ; Hemispheric asymmetry ; Imprinting
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The distribution of cholinergic receptor binding sites was studied in certain areas of the chick brain, especially that part (IMHV) of hyperstriatum ventrale which has previously been implicated in the imprinting process. There was relatively little binding of [125I]-α-bungarotoxin in this region, as shown using an autoradiographic technique. In contrast muscarinic receptor sites, with an affinity for [3H]-quinuclidinyl benzilate (QNB), are present in relatively high concentration in a medial forebrain sample containing IMHV and also in a visual projection area, the hyperstriatum accessorium (HA). To assess the effects of imprinting on the concentration of QNB binding sites 26 young chicks were exposed to an imprinting stimulus (a pulsing red light) for 20 min. Thirteen of the chicks were returned to the dark and the other 13 were trained for a further 100 min. There was no effect of further training on specific QNB binding in HA or in the medial forebrain sample. In undertrained chicks there was a positive correlation between QNB binding in the medial forebrain sample of the left hemisphere and that in the right; there was no such relationship in overtrained birds. Mean QNB binding in the right medial forebrain sample was greater than in the left by 21%. There was no such hemispheric asymmetry in HA.
    Type of Medium: Electronic Resource
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