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  • Cell & Developmental Biology  (1)
  • Key words Metacarpal fracture • Analysis of literature • Conservative treatment • Operation  (1)
  • Life and Medical Sciences  (1)
  • Manganese  (1)
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  • 1
    ISSN: 1433-044X
    Keywords: Key words Metacarpal fracture • Analysis of literature • Conservative treatment • Operation ; Schlüsselwörter Mittelhandbruch • Literaturrecherche • Konservative Therapie • Operation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Da auch heutzutage die Behandlung der Mittelhandbrüche kontrovers diskutiert wird, wurde eine Literaturanalyse durchgeführt, um die unterschiedlichen Therapien, Indikationen und deren Ergebnisse aufzuzeigen. Aus der Literatur vom 1. 1. 1984–31. 03. 1996 wurden Daten von 1602 nachuntersuchten Patienten verglichen; 522 operativ versorgte Patienten wurden mit Kirschner (K)-Drähten, Schrauben, Plättchen, Cerclage oder Minifixateur externe behandelt. Die konservativen Ansätze reichen von der Immobilisation bis hin zu unterschiedlichsten frühfunktionellen Methoden mit verschiedensten Hilfsmitteln oder gar ohne jede Fixation des Bruches. Die frühfunktionelle Therapie mit einem Brace kam bei 95 % zu sehr guten und guten Ergebnissen, hatte aber eine Therapieabbruchrate von bis zu 23 % aufgrund von lokalen Druckstellen und Hautnekrosen (3 %). Die teilweise Ruhigstellung mit unterstützendem Handcast, Tape etc. kam bei 94 % zu sehr guten und guten Ergebnissen. Hierbei traten keine Komplikationen auf. Jeweils 85 % sehr gute und gute Resultate erzielten die operativen Verfahren und die Immobilisationsbehandlung. Die Reposition von Mittelhandknochen (MHK)-V-Frakturen hatte nur bei 15 % der Patienten Erfolg. Metarkapalefrakturen mit Dislokationen unter 30 °, einer Verkürzung von weniger als 5 mm, einer Rotationsfehlstellung unter 10 °, keiner Gelenkstufe und ohne relevantes Weichteiltrauma benötigen nach unseren Ergebnissen keine Operation und sollten auch nach den Ergebnissen der Literaturrecherche frühfunktionell behandelt werden. Bei Überschreitung dieser Grenzen ist eine primäre operative Therapie gerechtfertigt. Die Immobilisation von Mittelhandfrakturen über mehr als 3–4 Wochen ist nicht sinnvoll.
    Notes: Summary As the treatment of metacarpal fractures is today still a controversial subject, we conducted an analysis of the literature in order to present the different therapy guidelines, indications, and their results. The data from the follow-up of 1602 patients was taken from literature which dated from 1 January 1984 to 31 March 1996. A total of 522 patients who underwent surgery received K-wires, screws or external minifixateur. The conservative approaches ranged from immobilization to various methods of mobilization with different aids or without fixation of the fracture. The mobilization in a brace provided good to excellent results in 95 % of the cases; however, the failure rate of therapy was 23 % because of local bruises and skin necrosis (3 %). The mobilization with handcast, tape etc. attained good to excellent results in 94 % of the cases. Here, no complications occurred. Both the immobilization treatment and the surgery provided good to excellent results in 85 % of the cases. The reposition of fractures of the fifth metacarpal was successful in only 15 % of the cases. Fractures with dislocations below 30 °, a shortening of less than 5 mm, no rotational displacement or that below 10 °, no articular incongruency, and no relevant soft tissue trauma do not need surgery according to our results and should be treated with early mobilization as suggested by the survey. Beyond these limits a primary surgical therapy is justified. The immobilization of metacarpal fractures over a period of more than 3–4 weeks is not necessary.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1619-7089
    Keywords: Manganese ; Positron emission tomography ; Tracer kinetic modeling ; Myocardial perfusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract There is a need for a quantitative myocardial perfusion agent that does not require an on-site cyclotron. Early studies with manganese demonstrated that this trace metal is of potential use for myocardial imaging.52mMn can be produced in a52Fe-52mMn generator and is suitable for positron emission tomographic (PET) imaging. The purpose of this study was to evaluate52mMn with regard to its potential to quantitatively assess myocardial perfusion. Dynamic PET imaging was performed in six pigs with various doses of dipyridamole to increase blood flow. Retention (R) and model-basedK 1 values were correlated with microsphere blood flow. The models consisted of one (K 1,k 2) and two (K 1,k 2,k 3) tissue compartments. Anterior, lateral and septal regions showed a good myocardium-to-background ratio; the evaluation of the inferior wall was impaired by high liver uptake. Linear regression yielded the following equations:K 1=1.152 flow+0.059 (r=0.92),R=0.069 flow+0.034 (r=0.84). Based on these regressions,K 1 increased 2.7-fold andR 2.6-fold in the examined flow range of 0.5–2 ml/min/g (fourfold increase), demonstrating an underestimation of higher flow rates by both measures. It is concluded that52mMn allows the qualitative assessment of myocardial perfusion but does not meet the requirements of a quantitative myocardial perfusion agent.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 203 (1982), S. 47-54 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Renal vascular tubular relationships were studied in the marsupial Isoodon obesulus (the common brown bandicoot). The microcirculation was filled with colored silicone rubber by intra-arterial injection of the intact kidney. Nephrons were defined by the injection of silicone rubber of a contrasting color into the space of Bowman's capsule in thick, cleared slices of renal tissue. The details of the vascular tubular relationship in this marsupial are strikingly similar to relationships previously described in true mammalian kidneys. An unusual feature is a wide (600μ) glomerulus-free zone at the outer cortex. This zone contains the proximal and distal convoluted tubules of the most superficial cortical nephrons and is perfused by efferent vessels from glomeruli in superficial strata of the cortex.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
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