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  • 1
    Electronic Resource
    Electronic Resource
    Direct demonstration of the function of T cell subsets reactive with anti-T cell antibodies from SLE sera (1982)
    Springer
    Rheumatology international 1 (1982), S. 157-163 
    Details
    ISSN: 1437-160X
    Keywords: Anti-lymphocyte antibodies ; Systemic lupus erythematosus ; Suppressor T cell ; Monoclonal antibodies ; Anti-Ig coated dish
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Anti-lymphocyte antibodies obtained from patients with active systemic lupus erythematosus (SLE) were used in a solid-phase procedure performed at 37 °C to isolate two distinctive T lymphocyte subpopulations. Lymphocytes isolated in this way were characterized by a fivefold enrichment in cells with the T8 phenotype and a threefold diminution in cells with the T4 phenotype over the residual lymphocytes that did not react with the antilymphocyte antibodies. Evidence was obtained that the dominant class of anti-lymphocyte antibodies reacting at 37 °C were of the IgG class. The isolated lymphocyte population, both with and without Con A stimulation strongly suppressed B cell IgG secretion stimulated by pokeweed mitogen. In contrast, the residual cells enhanced Ig secretion in the same system. These results indicate that the positively selected T cells with anti-lymphocyte antibodies from active SLE sera are mainly suppressor T cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00541170
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  • 2
    Electronic Resource
    Electronic Resource
    Synthesis of RNA in L cells infected with mengo virus (1963)
    Philadelphia : Wiley-Blackwell
    Journal of Cellular and Comparative Physiology 62 (1963), S. 179-192 
    Details
    ISSN: 0095-9898
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1030620207
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    Paper (German National Licenses)
    Fulltext
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