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  • 1
    Digitale Medien
    Digitale Medien
    Immunohistochemistry of primary central nervous system malignant rhabdoid tumors: report of five cases and review of the literature (1996)
    Springer
    Acta neuropathologica 91 (1996), S. 578-586 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Key words Malignant rhabdoid tumor ; Immunohistochemistry ; Central nervous system
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Malignant rhabdoid tumors (MRT) are characterized by a typical light microscopic morphology with uniformly round tumor cells, vacuolated cytoplasm with occasional round, hyaline intracytoplasmic, periodic acid-Schiff-positive inclusions, vesicular nuclei with prominent nucleoli and positive immunoreactivity for vimentin. The histogenesis of MRT is controversial. Five cases of primary central nervous system (CNS) rhabdoid tumors in children are presented. Immunohistochemical, light and electron microscopic features are compared with primary CNS malignant rhabdoid tumors reported in the literature. Expression of various neurofilaments in our cases of primary CNS rhabdoid tumors was prominent and we therefore favor a neural differentiation of extrarenal intracerebral rhabdoid tumors.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s004010050470
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Giant axonal neuropathy (1987)
    Springer
    Acta neuropathologica 73 (1987), S. 138-144 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Giant axonal neuropathy ; Intermediate filaments ; Rosenthal fibers
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Giant axonal neuropathy (GAN) is a disease characterized by a slowly progressive neuropathy and signs of central involvement, manifested by visual impairment, corticospinal tract dysfunction, ataxia, and dementia. Pathological hallmarks of the disease include axonal swellings packed with neurofilaments in both peripheral and central nervous systems, and accumulations of intermediate filaments in Schwann cells, fibroblasts, melanocytes, endothelial, and Langerhans cells. Rosenthal fibers, sometimes appearing in masses and mimicking Alexander's disease, emerge as a conspicuous characteristic in longstanding GAN.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00693779
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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