ISSN:
1432-0533
Keywords:
Key words Malignant rhabdoid tumor
;
Immunohistochemistry
;
Central nervous system
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Malignant rhabdoid tumors (MRT) are characterized by a typical light microscopic morphology with uniformly round tumor cells, vacuolated cytoplasm with occasional round, hyaline intracytoplasmic, periodic acid-Schiff-positive inclusions, vesicular nuclei with prominent nucleoli and positive immunoreactivity for vimentin. The histogenesis of MRT is controversial. Five cases of primary central nervous system (CNS) rhabdoid tumors in children are presented. Immunohistochemical, light and electron microscopic features are compared with primary CNS malignant rhabdoid tumors reported in the literature. Expression of various neurofilaments in our cases of primary CNS rhabdoid tumors was prominent and we therefore favor a neural differentiation of extrarenal intracerebral rhabdoid tumors.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004010050470
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