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  • Purkinje cells  (3)
  • Cerebellärer Cortex  (2)
  • Instrumental Conditioning  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 38 (1980), S. 363-373 
    ISSN: 1432-1106
    Keywords: Passive movements ; Cerebellar cortex ; Climbing fiber input ; Purkinje cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Discharges of Purkinje cells (PCs) with simple (SS) and complex spikes (CS) in the c1zone of lobule Vc of the anterior lobe of the cerebellar cortex were analyzed in the decerebrate cat during a passive movement of the cat forepaw. The CS of the PC responded differentially and/or proportionally to the position of the extremity, amplitude of the movement, velocity and acceleration. Inphase and outphase responses of the climbing fiber (CF) system to sinusoidal movements could depend on the position of the extremity within the operational range. From these results we deduce that peripheral events can be signalled by the CF system. The possible function of the interaction between the two inputs at the PC level is discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 314 (1970), S. 68-85 
    ISSN: 1432-2013
    Keywords: Cerebellärer Cortex ; Faserentladungen ; Evoked Potentials ; Cerebellar Cortex ; Fiber Responses ; Evoked Potentials
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary To investigate the relationship between the surface evoked potentials of the superficial radial nerve and the splanchnic nerve, and the fiber evoked responses of the cerebellum of the cat was the purpose of the present study. The discharges of the mossy fibers, climbing fibers and Purkinje cell axons were identified and their relationship with the surface-potentials established. The mossy fibers fire with train of spikes in different groups, which probably correspond to impulses transmitted through fibers of different conduction velocities and synchronously with the first positivity of the evoked potential. Climbing fibers respond synchronously with the development of the sharp negative deflection of the evoked potentials and were, for the first time, identified. Finally, the Purkinje cell axons exhibited the same firing pattern as the Purkinje cells. Cutaneous and visceral afferents use not only common elements of the cerebellar cortex but also common pathways, in spite of measurable differences between both afferents.
    Notes: Zusammenfassung Der Zweck der vorliegenden Arbeit war die Beschreibung der Beziehung zwischen den Oberflächen-Evoked Potentials, ausgelöst durch Reizung des N. radialis superficialis und des N. splanchnicus und den evozierten Faserentladungen am Kleinhirn der Katze. Die Entladungen der Moosfasern, Kletterfasern und Axone der Purkinje-Zelle wurden identifiziert und ihre Beziehung zu den Oberflächenpotentialen festgestellt. Die Moosfasern feuern mit Spikesalven und in verschiedenen Gruppen. Diese entsprechen wahrscheinlich Impulsen, die von Fasern mit verschiedener Leitungsgeschwindigkeit fortgeleitet werden und die synchron mit der ersten Positivität der Evoked Potentials sind. Die Kletterfasern stehen in zeitlicher Beziehung zu der Entwicklung der scharfen negativen Ablenkung des EPs und werden zum ersten Male identifiziert. Schließlich weisen die Axone der Purkinje-Zelle dieselben Entladungsmuster auf wie die Purkinje-Zelle selbst. Cutane und viscerale Afferenzen benutzen nicht nur gemeinsame Elemente des cerebellären Cortex, sondern wahrscheinlich auch gemeinsame Leitungswege, obwohl es quantitative Differenzen zwischen beiden Afferenzen gibt.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2013
    Keywords: Cerebellärer Kortex ; Lernen am Erfolg ; Licht-Dunkelheit-Diskrimination ; Cerebellum ; Instrumental Conditioning ; Light-Dark Discrimination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Ten adult cats were used as subjects in a study which was designed to investigate the effects of cortical ablations of the cerebellar hemispheres upon learning and retention of a light-dark discrimination task. The discrimination task was instrumentally conditioned in food-deprived cats. The results of this study showed that unilateral or bilateral ablations of the cerebellar hemispheres have no effects upon retention of a learned discrimination task. The data further indicated that bilateral ablations of the cerebellar hemispheres seem to retard learning of a discrimination task during the first 5 days of the learning period. This latter effect was interpreted to be due to a dynamic period of compensation, during which, asCarrea andMettler [3] assumed, the cerebral cortex takes over the functions of the ablated parts of the cerebellum.
    Notes: Zusammenfassung Zehn Katzen wurden als Versuchstiere in einem Experiment benutzt, welches die Einflüsse der Entfernung der corticalen cerebellären Hemisphären auf das Erlernen und Behalten einer Licht-Dunkelheit Diskrimination untersuchte. Die Diskriminationsaufgabe wurde bei hungrigen Katzen nach der Skinner Methode durchgeführt. Die Ergebnisse dieser Studie zeigten, daß unilaterale oder bilaterale Entfernungen der cerebellären corticalen Hemisphären keinen Einfluß auf das Behalten der erlernten Diskriminationsaufgabe hatten. Dagegen schien die bilaterale Entfernung der cerebellären corticalen Hemisphären das Erlernen der Diskriminationsaufgabe zu verzögern, besonders während der ersten 5 Tage der Lernperiode. Es wurde angenommen, daß dieser einfluß auf einer dynamischen Kompensationsperiode beruht, während der, wieCarrea undMettler [3] vermuteten, der cerebrale Kortex die Funktion der entfernten Teile des Kleinhirns übernimmt.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-2013
    Keywords: Cerebellärer Cortex ; Instrumentelle Konditionierung ; Licht-Dunkelheit-Diskrimination ; Cerebellar Cortex ; Instrumental Conditioning ; Light-Dark-Discrimination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Eighteen cats were used as subjects in a study which investigated the effects of bilateral cortical cerebellar hemispheric ablations upon light-dark discrimination learning. From the operated control group (8 animals), 5 were tested two weeks and 3 three weeks postoperatively. From the experimental group (10 animals) 4 were tested two weeks and 6 three weeks postoperatively. The discrimination task consisted of an instrumentally conditioned bar-pressing response. The results showed that almost during the entire 23-day learning period, the experimental cats performed more poorly on the discrimination task than their controls. It is hypothesized that the difference between the two groups of animals derives from the disturbance (caused by the ablation) of the connections between the cerebellum and other structures involved in the habituation process.
    Notes: Zusammenfassung 18 Katzen wurden als Versuchstiere in einem Experiment benutzt, welches den Einfluß der bilateralen Entfernung des corticalen Teils der cerebellären Hemisphären auf das Erlernen einer Licht-Dunkelheit-Diskrimination untersuchte. Von der operierten Kontrollgruppe (8 Tiere) wurden 5 zwei Wochen und 3 drei Wochen nach der Operation getestet. Von der experimentellen Gruppe (10 Tiere) wurden 4 zwei Wochen und 6 drei Wochen nach der Operation getestet. Die Diskriminationsaufgabe bestand aus Hebeldrücken nach der Skinner-Methode. Die Ergebnisse zeigten, daß die experimentellen Tiere fast während der ganzen Lernperiode (23 Tage) weniger Diskriminationsvermögen aufweisen als die Kontrolltiere. Es wurde vermutet, daß dieser Unterschied zwischen den experimentellen Tieren und den Kontrolltieren darauf beruht, daß die Entfernung eines Teils des cerebellären Cortex die Verbindungen zu Strukturen, die bei dem Habituationsprozeß eine Rolle spielen, stört.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 31 (1978), S. 387-401 
    ISSN: 1432-1106
    Keywords: Passive movement ; Cerebellar cortex ; Mossy and climbing fiber input ; Granular cells ; Purkinje cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The responses of mossy fibers (MF), granular cells (GrC) and Purkinje cells (PC) were recorded in the cerebellum of the decerebrate cat during a passive movement about the forepaw wrist joint. Three main discharge patterns containing information about all the static and dynamic parameters of the movement were found. Simultaneous recording of complex spikes (CS) and simple spikes (SS) showed that the activity of PC can be modulated through either MF or CF input channels alone or both together. In the latter case SS and CS discharge most commonly showed an opposite behavior, in which the increase of the frequency of one type of spike was accompanied by a decrease of the frequency of the other type. Both inputs displayed tonic and phasic characteristics and all the qualitative discharge patterns observed. Therefore it was concluded that aside from differences in the discharge frequency, both inputs are able to directly signal peripheral events.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 42 (1981), S. 249-259 
    ISSN: 1432-1106
    Keywords: Passive movement ; Cerebellar cortex ; Climbing fiber and mossy fiber system ; Granule cells ; Purkinje cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In the decerebrate cat discharges of Purkinje cells with simple and complex spikes as well as granule cell discharges in the c1-zone of lobules Va, b and c of the cerebellar anterior lobe were analyzed during a passive movement of the cat's forepaw. Penetrations were made 50 μm apart along the mediolateral and parasagittal directions, the depth never exceeding 500 μm. The response of the Purkinje cells to the climbing fiber input was surprisingly constant, while simple spike responses of the same cells showed a great variability to the same input. The variability between granule cell discharges recorded at a 50 μm distance from each other was similar to that of the simple spikes of the Purkinje cell. It is assumed that because of a patchy distribution of excited granule cells, two neighbouring Purkinje cells may receive a different information via their parallel fiber inputs. This difference is considered to be responsible for the great variability of their responses to mossy fiber inputs.
    Type of Medium: Electronic Resource
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