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  • Electron microscopy  (3)
  • Microtubules  (3)
  • Development  (2)
  • Cerebellum  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Microtubules associated with nuclear pore complexes and coated pits in the CNS (1976)
    Springer
    Cell & tissue research 168 (1976), S. 445-453 
    Details
    ISSN: 1432-0878
    Keywords: Microtubules ; Nuclear pores ; Coated pits ; Coated vesicles ; Central nervous system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Using a new albumin prefixation technique, microtubules have been observed in close association with the nuclear pores of neurons and glia. Thus, microtubules may be involved in such phenomena as anchoring, migration or rotation of the nucleus or in chemical messenger transport between nucleus and cytoplasm. Microtubules are also seen running close to the coated pits of dendrites. The implications are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00215995
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Thyroidectomy induces coated pit formation on cerebellar mossy fiber terminals (1985)
    Springer
    Cell & tissue research 239 (1985), S. 627-631 
    Details
    ISSN: 1432-0878
    Keywords: Thyroidectomy ; Cerebellum ; Coated pit ; Mossy fiber terminal ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The influence that thyroid hormones have on the development of the cerebellar cortex is well known. Their absence in adults leads to important functional changes probably related to abnormalities in nerve terminal activity, although no morphological alterations have hitherto been described. Using ultrastructural morphometric methods, we have studied the effects of thyroidectomy on the cerebellar cortex mossy fiber terminals of adult rats with different survival periods. No significant changes in the volume and surface area of these terminals were found. The numbers of synaptic vesicles in groups 7, 15 and 30 days after thyroidectomy were significantly greater than in controls. A significant increase in coated pit formation was found when thyroidectomized groups were compared with controls. This increase is due to the lack of thyroxin since it can be counteracted by thyroxin administration. Whether this increased coated pit formation is a membrane retrieval mechanism or is related to the uptake of extracellular molecules remains to be determined.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00219241
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Marginal bundles of axoplasmic microtubules at nodes of Ranvier within muscle (1979)
    Springer
    Cell & tissue research 199 (1979), S. 281-288 
    Details
    ISSN: 1432-0878
    Keywords: Annular microtubules ; Nodes of Ranvier ; Nerve ; Axon ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Using a special albumin technique, nodes of Ranvier have been examined within frog skeletal muscle, sciatic nerve and rat and frog cerebrum. Initial segments have been examined in cerebrum of frog and rat. Microtubules usually run longitudinally through these regions, but within the bare area of the intramuscular node of Ranvier, annular or helical bundles of microtubules run in a marginal band at right angles to the more centrally placed longitudinal microtubules. These nodal bare areas show a pronounced convexity and it is suggested that the annular microtubules serve to maintain this convexity during muscle contraction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00236139
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    On T-tubule openings at the sarcolemma of white fast-twitch muscle fibres in fish and frog (1978)
    Springer
    Cell & tissue research 188 (1978), S. 265-272 
    Details
    ISSN: 1432-0878
    Keywords: Muscles ; T-system ; Fish ; Frog ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In “white” muscle fibres of a teleost fish T-tubule openings may occur regularly at all Z-disc levels between adjacent peripheral myofibrils, the T-tubule openings thus occurring at a density of ca. 0.9 μm-2. In frog “white” fibres, T-tubule openings are infrequently seen in material fixed like the fish material. In material prepared according to the albumin method of Gray (1975, 1976 a, b) which renders the muscle fibres swollen, straight tubules or sometimes chains of vesicles instead are seen opening at the sarcolemmal surface. Such tubules occur at a higher density than expected from experiments with local activation of contraction. Lability and dynamics within the T-system normally and during fixation are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00222636
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Microtubules, dendritic spines and spine apparatuses (1980)
    Springer
    Cell & tissue research 208 (1980), S. 171-181 
    Details
    ISSN: 1432-0878
    Keywords: Microtubules ; Dendritic spine apparatus ; Synapse ; Development ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Using techniques for enhanced microtubular preservation, including albumin pretreatment (Gray, 1975), occipital cortex of rats was studied electron microscopically at various ages of development. A close structural relationship was seen between microtubules, sacs of SER and the postsynaptic “thickening” in primordial spines and with the dense “plate” material of spine apparatuses. Stereoscopic preparations in addition show a more complicated substructure than previously described for the “plate”. Microtubules may contribute to the formation of the “plate” of the spine apparatus which in turn is associated with the postsynaptic “thickening” of the mature spine. Possible functional correlates are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234868
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Synaptic development and microtubule organization (1983)
    Springer
    Cell & tissue research 231 (1983), S. 93-102 
    Details
    ISSN: 1432-0878
    Keywords: Synapses ; Microtubules ; Presynaptic dense projections ; Development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Using techniques for enhanced microtubular preservation (albumin pretreatment of Gray) occipital and pyriform cortices of rats were studied by electron microscopy at various stages of development. A close structural relationship was seen between microtubules (mts), focal membrane densities, synaptic vesicles, and presynaptic dense projections (pre-dps) during maturation. Mts were seen in the neonates to be focused onto the inner surface of immature axonic profiles merging or sometimes fragmenting there. Focal densities occur at these attachment sites and thereafter synaptic vesicles clothe the mts and abut onto these presumed primordial pre-dps. Thus, mts may contribute to the initial formation of pre-dps as well as their maintenance in the adult and may act to channel the first synaptic vesicles to the site of eventual synaptic contact and transmitter release.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00215777
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    Paper (German National Licenses)
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