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  • 1
    Digitale Medien
    Digitale Medien
    Fasting or dexamethasone treatment reduce protease content in rat lung mast cells and modulation of histamine synthesis by H3 receptors (1994)
    Springer
    Inflammation research 42 (1994), S. 7-12 
    Details
    ISSN: 1420-908X
    Schlagwort(e): Rat mast cell proteases ; Histamine presynaptic receptor ; Dexamethasone
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The sensitivity of mast cells to H3-receptor modulation was studied in rat lung under various hormonal conditions. The heterogeneity of mast cell subpopulations in rat lung was assessed by the tissue content of rat mast cell protease I (RMCP I) and rat mast cell protease II (RMCP II). After 24 h fasting, concentrations of RMCP I were unchanged whereas the concentration of RMCP II was significantly reduced by 49%. The [3H]histamine (HA) synthesis was concomitantly decreased by 35%. In addition, the modulation of [3H]HA, synthesis by the H3 receptor agonist, (R)α-methylHA and by the antagonist, thioperamide, observed in control rats, was lost in fasted rats. Single and repeated, administrations of dexamethasone did not influence RMCPI concentrations, but decreased the concentrations of RMCP II with a parallel decrease in [3H]HA synthesis. The inhibitory effect of (R)α-methylHA on [3H]HA synthesis was also reduced. These results suggest that a subpopulation of RMCP II-containing mast cells, very sensitive to environmental factors, could be the mast cells synthesizing HA in an H3-receptor-dependant manner.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02014292
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  • 2
    Digitale Medien
    Digitale Medien
    Effect of aldosterone and dexamethasone pretreatment on sodium transport in rat distal colon in vitro (1984)
    Springer
    Pflügers Archiv 400 (1984), S. 257-261 
    Details
    ISSN: 1432-2013
    Schlagwort(e): Rat colon ; Sodium transport ; Aldosterone ; Dexamethasone ; Amiloride
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Aldosterone and dexamethasone stimulate sodium absorption in the rat colon in vivo. In vitro, increased amiloride inhibitable short-circuit current (ISC) has been demonstrated following aldosterone or dexamethasone treatment. Since ISC bears no relationship to sodium flux (JNa) in the untreated rat colon, we measured JNa in partially stripped voltage clamped segments of rat distal colon. Our results demonstrate directly that continuous infusion of aldosterone or dexamethasone for 4–7 days stimulated amiloride inhibitable JNa by stimulating JNaM-S. The amiloride inhibitable portion of JNaM-S was highly correlated with and approximately equal to the amiloride inhibitable ISC. Amiloride had no effect in controls. We conclude that JNaM-S in the rat distal colon is only sensitive to mucosal amiloride after treatment with aldosterone or dexamethasone. the amiloride sensitive ISC in these treated tissues was a good measure of the amiloride sensitive JNa. Small differences between aldosterone and dexamethasone treatment were noted in the effect on transepithelial resistance, potential difference, and the ISC after amiloride.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00581556
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  • 3
    Digitale Medien
    Digitale Medien
    Ein naturwissenschaftliches Literaturkarussell: Interdisziplinäres (1990)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 24 (1990), S. XIII 
    Details
    ISSN: 0009-2851
    Schlagwort(e): Chemistry ; Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ciuz.19900240215
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  • 4
    Digitale Medien
    Digitale Medien
    Binding of end product in the fermentation of nucleotides (1973)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 15 (1973), S. 85-91 
    Details
    ISSN: 0006-3592
    Schlagwort(e): Chemistry ; Biochemistry and Biotechnology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Flavor enhancing nucleotides may be produced by streptomycetes. Mutants of streptomyces 772 were found to produce, under ordinary fermentation conditions, considerable amounts of 5′-IMP and 5′-XMP, but only traces of 5′-GMP. This was probably due to the feedback inhibition of the end product GMP. It was shown that through suitable fermentation techniques it was possible to overcome this internal control mechanism, leading to increased yields of 5′-GMP.
    Zusätzliches Material: 3 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bit.260150107
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  • 5
    Digitale Medien
    Digitale Medien
    Analytical model reduction of large scale linear dynamic systems (1977)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 23 (1977), S. 948-951 
    Details
    ISSN: 0001-1541
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: A class of dynamic model approximation techniques based on a frequency domain Taylor series expansion is presented. These methods yield low-order models and are analytical rather than computational in nature; that is, one can retain important parameters (which may be time varying) from the original model in functional form in the low-order model. This feature is very attractive for on-line updating of the simplified model and subsequent control of the process. An example for a tenth-order original model has shown that the analytical low-order models provide excellent approximations to the step response of the original system.
    Zusätzliches Material: 1 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aic.690230627
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  • 6
    Digitale Medien
    Digitale Medien
    Liquid holdup and dispersion in trickle-bed reactors (1976)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 22 (1976), S. 953-956 
    Details
    ISSN: 0001-1541
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aic.690220531
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  • 7
    Digitale Medien
    Digitale Medien
    A new tracer method for determination of liquid-solid contacting efficiency in trickle-bed reactors (1976)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 22 (1976), S. 894-904 
    Details
    ISSN: 0001-1541
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: A new tracer technique is reported for the determination of liquid-solid contacting efficiency and liquid holdup in trickle beds packed with small alumina particles. Holdup was a function of liquid mass velocity for both porous and nonporous packing. Contacting efficiency remained uniform at a level of 65%.
    Zusätzliches Material: 10 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aic.690220513
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  • 8
    Digitale Medien
    Digitale Medien
    Mechanical strength of acrylic bone cements impregnated with antibioticsPresented at the Seventh Annual International Biomaterials Symposium on Materials for Reconstructive Surgery, Clemson University, Clemson, South Carolina, April 26-30, 1975. (1976)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 10 (1976), S. 837-845 
    Details
    ISSN: 0021-9304
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin , Technik allgemein
    Notizen: Admixing of several antibiotic powders which were insoluble in methyl methacrylate did not decrease the compressive and diametral tensile strengths of two acrylic bone cements when tested after setting for 1 day and after leaching 40 days in water at 37°C. When antibiotics were added as water solutions, the included water resulted in a significant decrease in these bulk mechanical properties.Storage in water for 40 days caused surface irregularities only on specimens of the set antibiotic admixtures. Approximately 0.5% of the admixed dosage of these water-soluble antibiotics could be leached from the set cements. The observed surface channels, presumably left by the loss of antibiotic, suggest further study of surface-sensitive mechanical properties may be needed.The bulk mechanical strengths presented here are conclusive only for the particular combinations of antibiotics and cements investigated, and should not be generalized at this time to any or all antibiotic admixtures or other mechanical properties.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jbm.820100603
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  • 9
    Digitale Medien
    Digitale Medien
    The functional relationship scan in tandem mass spectrometry (1988)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 23 (1988), S. 579-584 
    Details
    ISSN: 0030-493X
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: A type of tandem mass spectrometric scan is described in which m1 +, m2 + and m3, defined in terms of the process m1 + → m2 + + m3, are all varied while maintaining some prescribed relationship between them. The scan can be viewed as a variant upon the neutral loss scan in which the constant mass difference between parent and daughter ion masses is replaced by some other functional relationship. Specific examples of this scan are provided in two simple applications: (i) symmetrical proton-bound dimers are recognized using the functional scan m2 = (m1 + 1)/2; and (ii) symmetrical Diels-Alder adducts comprised of diene and dienophile of equal masses are recognized in mixtures using the scan function m2 = (1/2)m1.
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/oms.1210230805
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