ISSN:
0021-8995
Schlagwort(e):
Chemistry
;
Polymer and Materials Science
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
,
Maschinenbau
,
Physik
Notizen:
Chitosan was chemically modified by alkylation with N-(2-bromoethyl) phthalimide, N-(3-bromopropyl) phthalimide, and N-(4-bromobutyl) phthalimide. The resulting N-(phthalidimidoalkyl) chitosans were treated with hydrazine to remove the phthalidimido group resulting in the final N-(aminoalkyl) chitosan products. For comparison purposes, poly(vinyl alcohol) (PVA) was alkylated with N-(3-bromopropyl) phthalimide, then treated with hydrazine to give the N-(3-aminopropyl) PVA product. All alkylation products were characterized by solution 1H- and 13C-NMR and by solid-state CP-MAS 13C-NMR. The above synthetic polymer derivatives, as well as chitosan, polyallyl amine, and polyethylen-imine, were used to form membrane coatings around calcium alginate beads in which blue dextran of molecular weight 7.08×104 or 26.6×104 was entrapped. These microcapsules were prepared by extrusion of a solution of blue dextran in sodium alginate into a solution containing calcium chloride and the membrane polymer. Membrane integrity and permeability were assessed by measuring the elution of the blue dextran from the capsules, spectrophotometrically. © 1993 John Wiley & Sons, Inc.
Zusätzliches Material:
8 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/app.1993.070500216
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