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  • 1
    Electronic Resource
    Electronic Resource
    Central pharmacological control of corticosterone secretion in the intact rat. demonstration of cholinergic and serotoninergic facilitatory and α-adrenergic inhibitory mechanisms (1980)
    Springer
    Psychopharmacology 71 (1980), S. 213-217 
    Details
    ISSN: 1432-2072
    Keywords: Corticosterone ; Muscarinic agonists ; Serotoninergic agonists ; α-Adrenoceptor agonists ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A method is described for demonstrating the hypothalamic control of corticosterone in the intact rat. Oxotremorine 0.01–0.05 mg/kg IP and 5-hydroxy-l-tryptophan 1–50 mg/kg IP raise plasma corticosterone levels in dose-related fashion. The oxotremorine response is blocked by atropine 1 mg/kg SC and the 5-hydroxy-l-tryptophan response by mianserin 10 mg/kg IP. α-Methylparatyrosine methyl ester 400 mg/kg IP raises plasma corticosterone levels 14–16 h later. This rise can be suppressed by clonidine 0.01–0.05 mg/kg IP and this suppression is antogonized by piperoxane 5–50 mg/kg IP. Apomorphine 5 mg/kg IP does not lower plasma corticosterone levels in rats pre-treated with α-methylparatyrosine. The response to oxotremorine cannot be blocked by atropine methylbromide or by mianserin. The response to 5-hydroxy-l-tryptophan is unaffected by benserazide or atropine sulphate. These data suggest separate cholinergic and serotoninergic facilitation of corticosterone release in the intact rat. The stimulating drugs used appear to be acting centrally. The data also support the presence of a noradrenergic inhibitory system mediated by α-adrenoceptors. Dopaminergic receptors appear to play no part in the central control of corticosterone secretion after pre-treatment with α-methylparatyrosine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00433054
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  • 2
    Electronic Resource
    Electronic Resource
    Leucocyte values in rats and mice following carbon dioxide euthanasia (1991)
    Springer
    Comparative clinical pathology 1 (1991), S. 233-235 
    Details
    ISSN: 1433-2981
    Keywords: Carbon dioxide ; Euthanasia ; Leucocytes ; Mice ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Leucocyte counts obtained from Wistar rats and CD1 mice following euthanasia with carbon dioxide were compared to leucocyte values obtained using other agents for anaesthesia or euthanasia. In rats, following euthanasia with carbon dioxide, lymphocyte and neutrophil counts in samples taken from the heart were significantly raised compared with sodium barbiturate euthanasia. In mice, following carbon dioxide, total leucocyte counts from brachial plexus were significantly lower than other collection sites. Lymphocyte counts from vena cava and brachial plexus were also significantly lower than other sites.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00235378
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  • 3
    Electronic Resource
    Electronic Resource
    Preliminary studies with an SLS method for haemoglobin determination in three species (1992)
    Springer
    Comparative clinical pathology 2 (1992), S. 101-102 
    Details
    ISSN: 1433-2981
    Keywords: Haemoglobinometry ; Sodium lauryl sulphate ; Rats ; Dogs ; Mice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A commercially available sodium lauryl sulphate reagent was used to determine haemoglobin values in three species, and these values were compared with results obtained by a cyanmethaemoglobin method with the same haematology analyser. Correlation of the two methods was satisfactory for samples obtained from healthy rats and dogs. For mouse samples, the correlation between methods was poorer than for the other two species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00186269
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  • 4
    Electronic Resource
    Electronic Resource
    The effect of repeated electroconvulsive shocks on growth hormone secretion and growth hormone responses to clonidine in the intact rat (1982)
    Springer
    Psychopharmacology 76 (1982), S. 98-100 
    Details
    ISSN: 1432-2072
    Keywords: Electroconvulsive shock ; Growth hormone ; Clonidine ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect of repeated electroconvulsive shocks (ECS) on growth hormone (GH) secretion was studied in rats. Male Sprague-Dawley animals were given one ECS daily for 10 days under halothane anaesthesia. Control animals were anaesthetised only. GH secretion was studied 24 h after the last ECS or sham procedure. Background GH secretion was significantly greater in ECS-treated than in sham-treated animals (P〈0.001). The GH response to IV clonidine (0.01–0.1 mg/kg) did not differ between the two groups. The size of the GH response was not directly related to the basal GH secretion and could not be explained in terms of it.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00430767
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  • 5
    Electronic Resource
    Electronic Resource
    The effect of repeated electroconvulsive shock on corticosterone responses to centrally acting pharmacological stimuli in the male rat (1980)
    Springer
    Psychopharmacology 71 (1980), S. 205-212 
    Details
    ISSN: 1432-2072
    Keywords: Electroconvulsive shock ; Corticosterone ; Muscarinic agonists ; Serotoninergic agonists ; α-Adrenoceptor agonists ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect of repeated and single electroconvulsive shocks (ECS) on the corticosterone response to pharmacological stimuli has been studied in male rats. Plasma corticosterone concentrations are elevated by oxotremorine, a muscarinic agonist, and by 5-hydroxy-l-tryptophan, a precursor of serotonin. Both these agonists probably stimulate corticotrophinreleasing-factor release from the hypothalamus. The log dose-response curves of the corticosterone response to oxotremorine and to 5-hydroxy-l-tryptophan are shifted to the left after a single ECS given daily for 10 days compared with sham-shocked controls. Plasma corticosterone concentrations are elevated by treatment with α-methyl-p-tyrosine methyl ester (400 mg/kg IP). This rise is suppressed by clonidine. The log dose-response curve for the corticosterone response to clonidine after α-methyl-p-tyrosine methyl ester is also shifted to the left by repeated ECS, compared with controls. There is no difference in the corticosterone response of ECS and sham-treated groups given vasopressin, which is thought to act directly on the pituitary to release ACTH. A single ECS produces a slight enhancement of the response to 5-hydroxy-l-tryptophan, a slight decrease in the response to oxotremorine and no change in the response to clonidine after α-methyl-p-tyrosine. The disappearance of the difference in response between ECS and sham-treated animals was also studied 1,3, and 6 days after a series of ten ECS or sham procedures. Significant differences in the corticosterone responses to oxotremorine, 5-hydroxy-l-tryptophan and clonidine after α-methyl-p-tyrosine between ECS and sham-treated animas were found 24 h after the last ECS or sham shock. These differences were in decline 3 days after the last procedure and had completely disappeared by day 6. The decline was largely due to an increase in plasma corticosterone responsiveness to pharmacological stimuli of the shamshocked controls. Responses in the ECS-treated groups remained constant. It is apparent that the anaesthetic procedure suppresses the effect of oxotremorine, 5-hydroxy-l-tryptophan and clonidine after α-methyl-p-tyrosine on corticosterone concentrations in plasma. This effect is spontaneously reversible. Repeated ECS reverses the effect of the anaesthetic procedure but produces no reversible enhancement of its own.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00433053
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  • 6
    Electronic Resource
    Electronic Resource
    Radical initiated homo- and copolymerization of N,N,N′N′-tetra(2-hydroxypropyl)ethylene diamine methacrylate (1990)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 28 (1990), S. 949-953 
    Details
    ISSN: 0887-624X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pola.1990.080280421
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  • 7
    Electronic Resource
    Electronic Resource
    Über die Einwirkung von Titansäureanhydrid auf Natriumkarbonat (1903)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 37 (1903), S. 332-336 
    Details
    ISSN: 0863-1778
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 4 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19030370124
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  • 8
    Electronic Resource
    Electronic Resource
    Alkyl cyanoacrylates as space filling bone adhesives (1992)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 3 (1992), S. 207-210 
    Details
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Higher chained alkyl cyanoacrylates have potential to function efficiently as space filling, hydrophobic, viscoelastic, biocompatible, and rapidly polymerizing bone adhesives. Hence they may be useful in applications where a void has to be filled, such as replacement of the intervertebral disc. To assess their applicability as space filling material in such an pplication, three alkyl cyanoacrylates; methoxyethyl cyanoacrylate, isobutyl cyanoacrylate, and isoamyl cyanoacrylate have been evaluated in this study. The bonding strength of these cyanoacrylates to bone in a space filling situation have been measured. The results indicate the bond strength of isoamyl cyanoacrylate (0.13 MPa) to be significantly (p 〈 0.05) lower compared with methoxyethyl cyanoacrylate (0.33 MPa) and isobutyl cyanoacrylate (0.37 MPa). There was no significant difference in the bond strengths of isobutyl cyanoacrylate and methoxyethyl cyanoacrylate.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jab.770030307
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  • 9
    Electronic Resource
    Electronic Resource
    Graft copolymerization of collagen with N, N, N′, N′-tetra (2-hydroxypropyl) ethylene diamine methacrylate by use of potassium persulfate as an initiator (1990)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 40 (1990), S. 1541-1545 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Graft copolymerization of collagen with N,N,N′,N′-tetra (2-hydroxypropyl) ethylene diamine methacrylate (THPEDM) was carried out in an aqueous medium using potassium persulfate as the radical initiator. Collagen-g-poly(THPEDM) was characterized by the percent yield and the copper chloride test. The percentage of grafting was determined as functions of concentration of monomer, concentration initiator, reaction time, and temperature.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1990.070400911
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  • 10
    Electronic Resource
    Electronic Resource
    Further aspects of the thermal degradation of epoxide resins (1967)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 11 (1967), S. 1009-1026 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: This paper describes an investigation into the degradation of a purified epoxide based on the diglycidyl ether of bisphenol A hardened with p,p′-diaminodiphenylmethane. The method used was that of hot-wire pyrolysis followed by gas chromatography. Special attention was given to the problem of solid residues formed on the pyrolyzer tube, and evidence was found that these probably contain oligomers. Resonance-stabilized free radicals also appear to be formed, and evidence is found to support the idea of dehydration during degradation, originally put forward by Lee. An attempt, based on first principles, is made to explain the degradation of epoxides, using evidence from previous work as well as that described in this paper.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1967.070110701
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