ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The kinetics of the hydrolysis of some substituted benzylidene benzoichydrazide 1a-e in 40% (v/v) ethanol buffer mixture have been investigated by differential pulse polarography. The mechanism of the hydrolysis in acidic buffer solutions is discussed.The catalysis by H⊕ involves the conversion of the hydrazide compound to its conjugated acid in a rapid preequilibrium step followed by a slow attack of water. The effects of pH, water, organic solvents and molecular structure on the reaction rate and the activation are investigated.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19863280525
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