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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 51 (1995), S. 245-248 
    ISSN: 1420-9071
    Keywords: Protein synthesis ; CA2+ activity ; ischemia ; hippocampus ; slice ; in vitro
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Increase in intracellular calcium concentration is a prominent feature of ischemia and has been considered a major factor in the initiation of ischemic pathology, which involves inhibition of protein synthesis. A reduction of calcium ion activity during and immediately after in vitro ischemia did not prevent inhibition of protein synthesis in hippocampae slices. When slices were overloaded with calcium by NMDA receptor activation or by the calcium ionophore A23187, no significant inhibition of protein synthesis was observed. We conclude that calcium overload plays only a limited role in ischemic inhibition of protein synthesis.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 17 (1995), S. 325-327 
    ISSN: 1279-8517
    Keywords: Radiographs ; Colorcoding ; Monochromatic MoK α-radiation ; Intervertebral disc ; Chemonucleolysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les radiographies sont largement utilisées dans le domaine de la pathologie ostéo-articulaire. Des procédés spéciaux peuvent être utilisés pour améliorer la qualité de l'image. Nous rapportons une nouvelle technique radiographique qui utilise un rayonnement monochromatique de molybdène Kα associée à un codage couleur digital secondaire pour obtenir des images bien contrastées. Afin d'évaluer l'apport diagnostique de cette technique, des specimens de disques intervertébraux de cadavres ayant fait l'objet d'une chimio-nucléolyse par injection de chymopapaine ont été étudiés. Les radiographies des specimens réalisés avec un tube à rayons X avec anode en molybdène et un filtre de zirconium ont fait l'objet d'un traitement informatique et d'un codage couleur. Cette technique améliore la résolution et le contraste des images et ainsi l'analyse des modifications morphologiques.
    Notes: Summary Radiographs are used in a wide variety of musculoskeletal examinations. Special procedures are required to improve image quality. We report a new radiologic technique that uses monochromatic molybdenumK α-radiation together with secondary digital color-coding to produce well contrasted images of supporting tissue. In order to investigate the diagnostic capability of this approach we studied specimens of the intervertebral disc, harvested from cadavers undergoing chemonucleolysis following an injection of chymopapain. Radiographs of the specimen taken using a Mo X-ray tube with a zirconium filter were scanned into a computerised image-processing system and color-coded. This method improves resolution and contrast in the images and allows the differentiation of morphologic changes.
    Type of Medium: Electronic Resource
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