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  • Choline acetyltransferase  (1)
  • Cortisol  (1)
  • Methodological rigour  (1)
  • PACS: 25.55.Kr 2H-,3He- and 4He-induced charge exchange reactions – 14.20.Gk Baryon resonances with S = 0 – 24.10.Eq Coupled channel and distorted wave models  (1)
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Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Altered brain cholinergic enzymes activity in the genetically obese rat (1991)
    Springer
    Cellular and molecular life sciences 47 (1991), S. 833-835 
    Details
    ISSN: 1420-9071
    Keywords: Choline acetyltransferase ; acetylcholinesterase ; obesity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Genetically obese male Zucker rats (fa/fa) and their lean littermates (Fa/-) were used in this experiment. Fourteen-week-old obese and lean littermates were sacrificed and choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) enzymes were assayed in specific brain regions. The assays of these enzymes indicate that obese animals and a significantly lower ChAT activity in the cerebellum, pons, and cerebral cortex and a significant increase in ChAT activity in the thalamus and hypothalamus. Meanwhile, the cerebral cortex, cerebellum, midbrain, thalamus and hypothalamus of the obese animals showed significantly higher AChE activity than their lean littermates. It was concluded from this study that obesity may be associated with changes in the enzymes of the brain cholinergic system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01922466
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Inclusive 2(3He,t) reaction at 2 GeV (1999)
    Springer
    The European physical journal 6 (1999), S. 225-233 
    Details
    ISSN: 1434-601X
    Keywords: PACS: 25.55.Kr 2H-,3He- and 4He-induced charge exchange reactions – 14.20.Gk Baryon resonances with S = 0 – 24.10.Eq Coupled channel and distorted wave models
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: The inclusive 2(3He,t) reaction has been studied at 2 GeV for energy transfers up to 500 MeV and scattering angles from 0.250 up to 40. Data are well reproduced by a model based on a coupled-channel approach for describing the NN and NΔ systems. The effect of final state interaction is important in the low energy part of the spectra. In the delta region, the cross-section is very sensitive to the effects of Δ-N interaction and ΔN → NN process. The latter has also a large influence well below the pion threshold. The calculation underestimates the experimental cross-section between the quasi-elastic and the delta peaks; this is possibly due to projectile excitation or purely mesonic exchange currents.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100500050338
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The response of runners to arduous triathlon competition (1986)
    Springer
    European journal of applied physiology 55 (1986), S. 405-409 
    Details
    ISSN: 1439-6327
    Keywords: Cortisol ; Iron ; Maximal oxygen consumption ; Performance ; Endurance exercise
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary As very few of the competitors in a triathlon are truly specialist in more than one of the three disciplines, high levels of physical (and mental) stress may result during the course of the event. We investigated some of the physiological responses occurring in runners participating in an “Iron Man” triathlon consisting of canoeing (20 km), cycling (90 km) and running (42 km), in that sequence. Twenty-one male entrants volunteered as subjects for the study. Prior to the competition, maximal oxygen consumption ( $$\dot V_{{\text{O}}_{{\text{2max}}} }$$ ) was determined. Basal venous blood samples were collected on the day prior to the competition and post-exercise venous blood samples were collected within 5 minutes of completion of the race. Serum iron was significantly reduced from a mean basal value of 20.6 Μmol · l−1 to a mean value of 8.4 Μmol · l−1 after the race. Cortisol levels showed a 3 fold increase after the race. Gross $$\dot V_{{\text{O}}_{{\text{2max}}} }$$ (l · min−1) and mass standardised $$\dot V_{{\text{O}}_{{\text{2max}}} }$$ (ml · min−1 · kg−1) were both negatively correlated to cortisol levels after the race (p〈0.05). Total performance time was not related to gross $$\dot V_{{\text{O}}_{{\text{2max}}} }$$ (l · min−1) but was well correlated to mass corrected $$\dot V_{{\text{O}}_{{\text{2max}}} }$$ (ml · min−1 · kg−1). The marked fall in serum iron may have been related to heavy sweating or prelatent iron deficiency. Chronic iron deficiency (without frank anaemia) can impair physical performance, although we were unable to show any significant correlation between serum iron level after the race and time taken to complete the event. The subjects with a lower $$\dot V_{{\text{O}}_{{\text{2max}}} }$$ (ml · min−1 · kg−1) had a higher cortisol concentration. In spite of a longer performance time, these subjects were apparently still exposed to greater physiological strain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00422741
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Technology assessment in healthcare: A means for pursuing the goals of biomedical engineering (1993)
    Springer
    Medical & biological engineering & computing 31 (1993), S. HTA3 
    Details
    ISSN: 1741-0444
    Keywords: Biomedical engineering ; Cost-effectiveness analysis ; Methodological rigour ; Policymaking ; Quality of life ; Technological innovation ; Technology assessment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The goals of biomedical engineering include the improvement of health and life quality of mankind. However, the contribution of biomedical engineering to those worthy ends must be more clearly related. Biomedical engineers should become more active in demonstrating to policymakers and other parties in healthcare the value of the contributions of healthcare technology. Technology assessment (TA) is a form of investigation designed to identify and evaluate the implications of technologies so as to inform policymaking. Among the important trends in TA that should be of special interest to biomedical engineers are the increasingly higher methodological standards for accepting evidence from clinical investigations, and the use of quality-of-life measures for determining how technologies affect people's lives.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02446885
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    Paper (German National Licenses)
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