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  • subarachnoid haemorrhage  (2)
  • Circadian rhythm  (1)
  • Diazo-positive urinary metabolites  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Early CT features of ruptured cerebral aneurysms of the posterior cranial fossa (1991)
    Springer
    Acta neurochirurgica 108 (1991), S. 34-39 
    Details
    ISSN: 0942-0940
    Keywords: CT finding ; subarachnoid haemorrhage ; posterior circulation aneurysm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This report describes our retrospective evaluation of CT features of the acute phase in 34 cases of ruptured cerebral aneurysms of the posterior cranial fossa. The results are as follows. 1. Examination of cisternal haematoma distribution revealed that SAH had extended to the supra- and infratentorial cisterns in 28 cases (82%). There were only 6 cases (18%) in which SAH was confined to the posterior cranial fossa only but even when there was subarachnoid haematoma in both the supra- and infratentorial cisterns, thick haematomas were seen at the periphery of the brain stem. In cases of vertebral artery-posterior inferior cerebellar artery aneurysms (VA-PICA AN), haematomas in the ambient cistern were thicker on the aneurysm side. In addition, in cases of basilar arterybifurcation (BA-Bifurcation AN) and basilar artery-superior cerebelli artery aneurysms (BA-SCA AN), there were many thick, highdensity haematomas in the interpeduncular cistern. 2. The rate of intracerebral haemorrhage was extremely low (1 patient). 3. The rate of intraventricular haemorrhage was high, and these haemorrhages demonstrated a reflux pattern. 4. The rate of hydrocephalus was high (76.5%) in comparison with that noted in association with SAH due to the rupture of anterior circulation aneurysms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01407664
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Correlation between CT findings and subsequent development of cerebral infarction due to vasospasm in subarachnoid haemorrhage (1980)
    Springer
    Acta neurochirurgica 55 (1980), S. 63-70 
    Details
    ISSN: 0942-0940
    Keywords: Cerebral aneurysm ; subarachnoid haemorrhage ; vasospasm ; computed tomography ; Hounsfield number
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have studied the correlations between computed tomograms (CT), clinical severity at the time of onset, and subsequent development of cerebral infarction due to vasospasm in 32 cases with subarachnoid haemorrhage secondary to rupture of cerebral aneurysms. It was found that the clinical severity could be judged by CT as shown by the amount of blood in subarachnoid space. Furthermore, it was possible to predict the subsequent occurrence of cerebral infarction by sequential findings of CT. A Hounsfield number of the high density area over 60 showed good correlation with the development of cerebral infarction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01808921
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    A field survey on the health status of workers in dye-producing factories (1977)
    Springer
    International archives of occupational and environmental health 39 (1977), S. 219-235 
    Details
    ISSN: 1432-1246
    Keywords: Anaemia ; Aromatic nitro-amino compounds ; Diazo-positive urinary metabolites ; Heinz bodies ; Hepatotoxicity ; Methemoglobinaemia ; Methemoglobin reductases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Health status of the workers in dye-producing plants were examined repeatedly in winter and in summer. The items studied cover 1) diazo-positive metabolites in urine 2) methemoglobinaemia, Heinz bodies, methemoglobin reductases and anaemia, and 3) liver function. The urinary diazo-positive metabolite level in the exposed was higher than that in the non-exposed and marked a conspicuous increase in summer as compared in winter, indicating significant intake of the aromatic nitro-amino compounds, while no significant methemoglobinaemia, Heinz bodies, anaemia nor disturbed liver function was observed in any group of the examinees. The results were discussed in connection with the dose-effect relationship, and compared with the experiences in the past.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00409368
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Chronopharmacological study of neuroleptics (1979)
    Springer
    Psychopharmacology 63 (1979), S. 131-135 
    Details
    ISSN: 1432-2072
    Keywords: Haloperidol ; Circadian rhythm ; Sedative effect ; Antiapomorphine effect ; Dopamine receptors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The circadian fluctuation of sedative effect of haloperidol was experimentally studied, as part of the series of investigations on circadian fluctuation of the effect of neuroleptics. Haloperidol of various doses was administered at various times during the day to rats which had been housed with strictly controlled lighting schedule and room temperature. It was shown that sedative effect of haloperidol was significantly affected by the time of day of administration, that is, there is a circadian fluctuation, and also that the variation pattern changed with different doses of this drug. In order to study the mechanism underlying this circadian fluctuation, time course changes in plasma and brain concentrations of the drug were measured. No significant difference in the concentrations was observed among the different times of administration. It was thus suggested that the circadian fluctuation of sedative effect of haloperidol might be due to the circadian rhythm of brain susceptibility to the drug. Antiapomorphine action of haloperidol was then examined using stereotyped behavior of the rat as an index. The result indicated the presence of the circadian fluctuation of antiapomorphine action which was in a pattern similar to the variation of the sedative effect of haloperidol. Based on the experimental results thus obtained, the generating mechanism for the circadian fluctuation of sedative effect of haloperidol was discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00429690
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    Paper (German National Licenses)
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