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  • 1
    ISSN: 1432-198X
    Keywords: Hereditary nephropathy ; Collagen type III glomerulopathy ; Type III collagen ; Familial haemolytic uraemic syndrome ; Nail-patella syndrome ; Glomerular extracellular matrix
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A new type of hereditary glomerulopathy was observed in ten children presenting with early and progressive glomerular symptoms, often associated with hypertension. Light microscopy showed a diffuse increase in the mesangial matrix and generalized widening of the capillary walls. Electron-microscopic examination of renal tissue, after phosphotungstic acid treatment, revealed the presence of fibrillar collagen within the mesangial matrix and the subendothelial aspect of the glomerular basement membrane, adjacent to normal lamina densa. Immunohistochemical studies identified the fibrillar collagen not usually present within the glomerular extracellular matrix as type III collagen. Clinical and family studies ruled out the diagnosis of nail-patella syndrome, an autosomal dominant disorder with typical extrarenal symptoms, which is also characterized by the presence of fibrillar collagen within the glomerular basement membranes. The poor renal outcome, the possible extrarenal haematological and pulmonary involvement and the transmission as an autosomal recessive trait strongly suggest that collagen type III glomerulopathy is a new type of hereditary disease. From the high incidence of superimposed haemolytic uraemic syndrome in patients or their siblings, it may be hypothetized that collagen type III glomerulopathy is the underlying defect in some of the familial cases of haemolytic uraemic syndromes.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Plant and soil 115 (1989), S. 129-134 
    ISSN: 1573-5036
    Keywords: error distributions ; image analysis ; root bulk density ; sampling simulation ; tree root system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract A new method has been proposed to estimate the total length in a sample, and it assumes that roots are cylinders with a given bulk density. The technique is based on the measurement of the length and diameter of small pieces of roots, and on the measurement of the bulk density of root sub-samples. An exact formulation is presented of the error distribution in estimating total root length. This leads to a simple formula which relates directly the variance of the root length estimates to both the number of roots used in estimating the root characteristics, and the number of sub-samples used in estimating the mean bulk density of the samples. This enables analyses of experimental designs with respect to sample size and accuracy.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Plant and soil 108 (1988), S. 267-274 
    ISSN: 1573-5036
    Keywords: image analysis ; sampling simulation ; tree root system ; root bulk density
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract A method is proposed for estimating the total length of a root system from sub-samples. This method is based on the measurement of the length and diameter of small pieces of roots, and on the measurements of the bulk density of root sub-samples. It is assumed that roots are cylinders with a given bulk density. The length and diameter of small root pieces are measured by image analysis. A weighted quadratic mean (W.Q.M.) root diameter is then calculated and used in estimating the root length. This W.Q.M. diameter is defined as the real mean diameter of an equivalent single root with the same length and volume as the tested root system. The accuracy of prediction is demonstrated for one theoretical root system. The standard deviation of estimation can be calculated using sampling simulations.
    Type of Medium: Electronic Resource
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