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  • 1
    Electronic Resource
    Electronic Resource
    Water uptake regulation in peach trees with split-root systems (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Plant, cell & environment 17 (1994), S. 0 
    Details
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The water uptake of 3- to 4-year-old peach trees ‘May-crest/Prunus Damas’ grown in an aerated nutrient solution was studied using a split-root system. Each container and the whole tree were weighed independently to measure water absorption by both parts of the root system and tree transpiration. Water potential of leaves was measured with a pressure chamber. Water potential of roots was estimated using root suckers sealed in plastic bags before the measurement. The nutrient solution was removed from one container so that half the root system was left in humid air for 48 h. Water potential of roots left in solution decreased, which (partly) maintained water absorption and thus transpiration. No modification of root hydraulic resistance was required to simulate the experimental results. Nevertheless, enhancement of absorption by the roots supplied with solution cannot compensate for the water loss by transpiration. Depletion of water from the plant essentially came from the non-absorbing roots. This was demonstrated by substituting vegetable oil for nutrient solution around one half of the split-root system, and by following the changes in root volume on the basis of Archimedes principle. Conflicting results in the literature about apparent changes in hydraulic resistance are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3040.1994.tb00306.x
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  • 2
    Electronic Resource
    Electronic Resource
    Four types of novelty–familiarity responses in associative recognition memory of humans (2004)
    Oxford, UK : Blackwell Science, Ltd
    European journal of neuroscience 19 (2004), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Animal studies show that, like inferior temporal neurons, dorsolateral prefrontal and parietal neurons often respond more strongly to individual novel than to individual familiar stimuli. It is currently unclear whether the novelty preference of prefrontal and parietal neurons extends to associative memory. We used electromagnetic recordings (MEG/EEG) and functional magnetic resonance imaging in two groups of healthy young adults to identify neural populations outside the inferior temporal cortex that exhibit associative novelty (stronger responses for new than for old configurations of two familiar items), and to distinguish them from associative familiarity (stronger responses for old than for new configurations of two familiar items). Subjects were required to learn and were later tested for associations based on the spatial configurations of two stimuli (a face and a tool). At test, learned (old) and rearranged (new) spatial stimulus configurations had to be discriminated. This recognition memory test could only be solved through the associative relationship between individual items because all component items of the stimulus configurations were equally familiar. In both imaging modalities, right dorsolateral prefrontal cortex and right parietal cortex showed an associative novelty response, whereas the right superior temporal cortex showed an associative familiarity response. With EEG/MEG only, the right extrastriate cortex showed an early associative familiarity and a late associative novelty response, whereas the opposite pattern emerged in bilateral frontopolar cortex. Thus, through a multimodal approach, it was possible to identify four types of associative novelty/familiarity responses outside the inferior temporal cortex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.2004.03253.x
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  • 3
    Electronic Resource
    Electronic Resource
    Kidney biopsy findings in cyclosporine-treated patients with insulin-dependent diabetes mellitus (1991)
    Springer
    Journal of molecular medicine 69 (1991), S. 354-359 
    Details
    ISSN: 1432-1440
    Keywords: Diabetes mellitus ; Cyclosporine ; Toxicity ; Risk factors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Renal biopsy specimens of 40 patients with recent-onset insulin-dependent diabetes mellitus treated with cyclosporine (CSA) for 6–29 months were examined. Cyclosporine-associated chronic vascular interstitial toxicity of moderate intensity was found in 10 patients (25%). The most prominent lesions were interstitial fibrosis and tubular atrophy. Arteriolopathy was less pronounced and glomerular damage unremarkable. A significant correlation exists between the extent of tubular atrophy and CSA trough whole blood levels. These data indicate that the development of CSA-associated chronic nephropathy is dose-dependent.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02115783
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  • 4
    Electronic Resource
    Electronic Resource
    Determination of phosphorus and zinc in lubricating oil additives (1975)
    Springer
    Microchimica acta 64 (1975), S. 493-501 
    Details
    ISSN: 1436-5073
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Methoden zur Halbmikrobestimmung von Phosphor und Zink in Schmierölzusätzen nach deren Verbrennung in einer mit Sauerstoff gefüllten 1-Literflasche wurden beschrieben. Die Phosphormethode beruht auf der Überführung des Phosphats in gelbes Phosphovanadomolybdat und dessen spektrophotometrischer Bestimmung bei 460 nm. Zink wird polarographisch nach Überführung in Tetrahydroxozinkat bestimmt, dessen Reduktions welle beim Anfangspotential von −1,10 V gegen eine ges. Kalomelelektrode gemessen wird. Eine Reihe von Ölzusatzproben mit geringen P-bzw. Zn-Gehalten (ca. 1,0% bzw. 1–2,5%) wurden mit befriedigenden Ergebnissen analysiert.
    Notes: Summary Methods are described for the semimicro-determination of phosphorus and zinc in lubricating oil additives, after combustion in a 1-litre flask filled with oxygen. The phosphorus method is based upon conversion of phosphate into yellow phosphovanadomolybdate and spectrophotometric measurement of its absorbance at 460 nm. Zinc is determined polarographically after conversion into the tetrahydroxozincate ion which yields, upon reduction at the D.M.E., a well-developed wave at a starting potential of −1,10 V vs. S. C. E. A variety of oil additive samples, with low phosphorus (ca. 1.0%) and zinc (1–2.5%) contents, was analysed satisfactorily.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01219218
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  • 5
    Electronic Resource
    Electronic Resource
    The roles of phosphorus deficiency and low food intake in the preservation of renal function in uraemic rats (1982)
    Springer
    Cellular and molecular life sciences 38 (1982), S. 681-682 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary While a diet deficient in phosphorus has a protective effect against kidney deterioration in uraemic rats, this effect, in fact, is more closely related to the reduction of food intake than tho the phosphorus load itself, even though the latter influenced the pattern of the renal lesions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01964093
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  • 6
    Electronic Resource
    Electronic Resource
    Infantile chronic tubulo-interstitial nephritis with cortical microcysts: variant of nephronophthisis or new disease entity? (1989)
    Springer
    Pediatric nephrology 3 (1989), S. 50-55 
    Details
    ISSN: 1432-198X
    Keywords: Infantile chronic renal failure ; Tubulo-interstitial nephritis ; microscysts
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Over a 15-year period we observed seven children (four girls, three boys) who presented within the first months of life with severe renal failure and acidosis, associated with hypertension in five patients and polyuria in four. In addition, one patient had a severe cholestatic liver disease. In two families, a similarly affected sibling had died previously. Four patients were referred with the clinical diagnosis of polycystic kidney disease because of moderate enlargement of kidneys, but renal imaging (intravenous pyelography and ultrasonography) did not confirm this diagnosis. A renal biopsy, performed in all patients, showed similar features characterized by a diffuse chronic tubulo-interstitial nephritis (TIN) and particularly by the presence of microcystic dilatation of proximal tubules and Bowman's space. Liver pathology was normal in two patients, including one with hepatomegaly. However, in the patient with cholestasis there was inflammatory portal fibrosis with mild duct proliferation. Progression of the renal disease was extremely rapid and all patients reached end-stage renal failure (ESRF) before the age of 2 years (11–22 months). Two children had successful renal transplants. Although this chronic TIN shares some features with nephronophthisis, we suggest that it represents a distinct entity both on clinical and morphological grounds. The specific clinical features of this disease are its early onset and rapid progression to ESRF. Pathologically, it differs from nephronophthisis by the absence of medullary cysts and thickened tubular basement membranes and by the presence of cortical microcysts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00859626
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  • 7
    Electronic Resource
    Electronic Resource
    Collagen type III glomerulopathy: a new type of hereditary nephropathy (1993)
    Springer
    Pediatric nephrology 7 (1993), S. 354-360 
    Details
    ISSN: 1432-198X
    Keywords: Hereditary nephropathy ; Collagen type III glomerulopathy ; Type III collagen ; Familial haemolytic uraemic syndrome ; Nail-patella syndrome ; Glomerular extracellular matrix
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A new type of hereditary glomerulopathy was observed in ten children presenting with early and progressive glomerular symptoms, often associated with hypertension. Light microscopy showed a diffuse increase in the mesangial matrix and generalized widening of the capillary walls. Electron-microscopic examination of renal tissue, after phosphotungstic acid treatment, revealed the presence of fibrillar collagen within the mesangial matrix and the subendothelial aspect of the glomerular basement membrane, adjacent to normal lamina densa. Immunohistochemical studies identified the fibrillar collagen not usually present within the glomerular extracellular matrix as type III collagen. Clinical and family studies ruled out the diagnosis of nail-patella syndrome, an autosomal dominant disorder with typical extrarenal symptoms, which is also characterized by the presence of fibrillar collagen within the glomerular basement membranes. The poor renal outcome, the possible extrarenal haematological and pulmonary involvement and the transmission as an autosomal recessive trait strongly suggest that collagen type III glomerulopathy is a new type of hereditary disease. From the high incidence of superimposed haemolytic uraemic syndrome in patients or their siblings, it may be hypothetized that collagen type III glomerulopathy is the underlying defect in some of the familial cases of haemolytic uraemic syndromes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00857536
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  • 8
    Electronic Resource
    Electronic Resource
    Haemolytic uraemic syndrome: prognostic factors in children over 3 years of age (1995)
    Springer
    Pediatric nephrology 9 (1995), S. 24-29 
    Details
    ISSN: 1432-198X
    Keywords: Haemolytic uraemic syndrome ; Prognosis ; Atypical form
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Previous studies have shown that age at onset of primary haemolytic uraemic syndrome (HUS) is a feature of prognostic significance, the disease being of much better outcome in paediatric patients younger than 3 years than in older children. In an attempt to find an explanation for such a difference, we analysed the clinical and pathological features of 42 children over 3 years of age who presented with HUS between 1955 and 1990 in our department. On the basis of the presence of a prodromal diarrhoea, we divided our patients into two groups: 21 children presented with the diarrhoea-associated (typical or D+) form of HUS, whereas 21 had the non-diarrhoea-associated (atypical or D-) form. Of the 42 children, 20 (47.5%) progressed to end-stage renal failure. However, our study shows that age at onset of HUS is not a prognostic feature per se. The difference in outcome between children and infants is most likely related to the high incidence of the atypical subset of HUS in children over 3 years, a subset that is very uncommon in infants. The ominous features which characterise this form of the disease are: (1) the absence of a diarrhoeal prodrome, (2) normal urine output, (3) marked proteinuria, (4) hypertension, (5) the occurrence of relapses or recurrences and (6) the presence of widespread and severe arteriolar changes on renal biopsy. The poor prognosis of the atypical form of HUS warrants the use of fresh-frozen plasma infusions and/or plasma exchange as early as possible in the course of the disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00858960
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  • 9
    Electronic Resource
    Electronic Resource
    Clinicopathological quiz (1987)
    Springer
    Pediatric nephrology 1 (1987), S. 245-247 
    Details
    ISSN: 1432-198X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00849299
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  • 10
    Electronic Resource
    Electronic Resource
    Ask the expert (1992)
    Springer
    Pediatric nephrology 6 (1992), S. 266-266 
    Details
    ISSN: 1432-198X
    Keywords: Diffuse mesangial sclerosis ; Bilateral nephrectomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00878364
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