Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Local cerebral glucose utilization and local cerebral blood flow in conscious rats after administration of flunarizine (1987)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 335 (1987), S. 680-685 
    Details
    ISSN: 1432-1912
    Keywords: Local cerebral blood flow ; 14C-Iodoanti-pyrine ; Local cerebral glucose utilization ; 14C-2-deoxy-glucose ; Flunarizine ; Conscious rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effects of the calcium entry blocker flunarizine on physiologic variables, local cerebral blood flow (LCBF) and local cerebral glucose utilization (LCGU) were investigated. LCBF and LCGU were determined in 37 anatomically discrete brain regions in lightly restrained, conscious rats, using the quantitative, autoradiographic 14C-iodoantipyrine and 14C-2-deoxyglucose techniques. While 5 mg/kg flunarizine given i. v. did not change any of the measured physiologic variables, flunarizine increased LCBF in nearly all gray matter structures compared with saline-treated controls. LCGU was not changed compared to controls. In control as well as in flunarizine-treated rats coupling between LCGU and LCBF was tight. The ratio of LCBF/LCGU was increased after treatment with flunarizine. The data suggest that under normal physiological conditions the calcium entry blocker flunarizine does not change neuronal activity, but exerts primarily a cerebral vasodilating action.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00166986
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Comparison of Different Di-tert-butyldimethyl-Silylated Cyclodextrins as Chiral Stationary Phases in Capillary Gas Chromatography (2000)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 23 (2000), S. 569-575 
    Details
    ISSN: 0935-6304
    Keywords: Enantioselective gas chromatography ; cyclodextrins ; heptakis(2,6-di-O-tert-butyldimethylsilyl)-β-cyclodextrin ; heptakis(2,6-di-O-tert-butyldimethylsilyl-3-O-methyl)-β-cyclodextrin ; heptakis(3,6-di-O-tert-butyldimethylsilyl-2-O-methyl)-β-cyclodextrin ; octakis(2,6-di-O-tert-butyldimethylsilyl-3-O-methyl)-γ-cyclodextrin ; thermodynamic parameters ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: ---Separation factors and thermodynamic data for the separation of various chiral analytes on different di-O-tert-butyldimethyl-silylated cyclodextrin derivatives are collected and described. Modifying the substitution pattern of the tert-butyldimethylsilyl group in position 2 and 3 or changing from β- to γ-cyclodextrin significantly affects the separation properties of the cyclodextrin derivatives.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
  • 3
    Electronic Resource
    Electronic Resource
    Frequency-dependent branching ratio in the infrared multiphoton photochemistry of diethyl carbonates (1990)
    Chichester : Wiley-Blackwell
    Journal of Physical Organic Chemistry 3 (1990), S. 567-574 
    Details
    ISSN: 0894-3230
    Keywords: Organic Chemistry ; Physical Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Unimolecular decomposition of 0·1 Torr of diethyl carbonate, diethyl-d5 carbonate and diethyl-d10 carbonate induced by irradiation with a CO2 TEA laser was investigated. In all cases only ethylene, ethanol and CO2 were obtained. In the case of diethyl-d5 carbonate, both ethylene-d4 and ethylene-d0 were observed together with the corresponding isotopic variants of ethanol. The chemical branching ratio was determined as a function of irradiation frequency and laser fluence by analysis of the ethylene-d0/ethylene-d4 ratio. RRKM theory applied to the branching ratio data requires very different average energies for two sets of fluence and frequency conditions that give identical total yields.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/poc.610030903
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Di-tert-butyldimethylsilylated cyclodextrins as chiral stationary phases: Thermodynamic investigations (1995)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Microcolumn Separations 7 (1995), S. 65-73 
    Details
    ISSN: 1040-7685
    Keywords: gas chromatography ; enantioselectivity ; cyclodextrins ; chiral separations ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Thermodynamic data, which are derived from measurements of separation factors at different temperatures for various chiral compounds, show some expected, but also some surprising effects concerning the mechanism of chiral recognition for the cyclodextrin derivatives investigated.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mcs.1220070110
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Intramolecular hydrogen isotope effect in the pyrolysis of diethyl carbonate-1,1,1,2,2-d5 (1983)
    New York, NY : Wiley-Blackwell
    International Journal of Chemical Kinetics 15 (1983), S. 461-468 
    Details
    ISSN: 0538-8066
    Keywords: Chemistry ; Physical Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The thermal unimolecular decomposition of diethyl carbonate-1,1,1,2,2-d5 has been examined in the high-pressure-limiting region. The observed chemistry is consistent with a simple, competitive two-channel model: The intramolecular isotope effect kH/kD has been determined, and the relative Arrhenius parameters for the two channels are given by \documentclass{article}\pagestyle{empty}\begin{document}$$ k_{\rm H} /k_D = (0.80 \pm 0.18)\,\exp [(1140 \pm 260){\rm cal/mol/RT}] $$\end{document} over the temperature range of 540-620 K. These Arrhenius parameters predict an isotope effect kH/kD = 5.4 at 300 K.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/kin.550150506
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...