ISSN:
1432-1017
Keywords:
Ion channels
;
Coupled Markov systems
;
Conditional distributions
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Physics
Notes:
Abstract The conditional distributions of openings and closings are computed for Markov schemes with two open and two closed states and with different pathways connecting the open and closed aggregates. The computation is performed for uncoupled schemes by directly applying the probability laws and by using a convolution algorithm for coupled schemes. The results show that, for coupled schemes, conditional distributions can be nonmonotonic functions of the dwell time duration. Simulations, illustrating how the difference between coupled and uncoupled models can be detected, are also reported.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00196593
Permalink
