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  • 1
    Electronic Resource
    Electronic Resource
    The self-inhibited leaky integrator: Transfer functions and steady state relations (1975)
    Springer
    Biological cybernetics 20 (1975), S. 51-59 
    Details
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Notes: Abstract We analyse a model for neural activity including forgetting and self-inhibition processes. The analysis concerns the static and dynamic performances. The theoretical predictions are compared with previously published experimental data on the neural encoding in the ommatidia of the Limulus lateral eye. We conclude that the analysed model could reproduce the experimental behaviour, but different models cannot be excluded. Moreover an independent normalisation factor has to be assumed to account for the experimental gains.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00350999
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Significance of phase-locking measurements as a test for neural encoding models (1978)
    Springer
    Biological cybernetics 30 (1978), S. 169-177 
    Details
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Notes: Abstract The significance of phase-locking measurements is discussed by comparing the phase-locking behaviour of three structurally similar neural encoders. They are the integrator with dead time, the self-inhibited integrate-and-fire system with a voltage dependent inhibitory quantum and the (already analysed) leaky integrator. The analysis shows significant differences between these systems; the loss of phaselocking as the input modulation depth increases is typical of the leaky integrator model. Moreover, the analysis performed brings out the importance of the problem of attractiveness in analysing the phaselocking of neural encoder models.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00337145
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Resonant response of a neural model and of limulus ommatidia to double frequency stimulation (1980)
    Springer
    Biological cybernetics 36 (1980), S. 137-142 
    Details
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Notes: Abstract Signals which are the sum of two sinusoids of frequencies v 1 and v 2 are used to stimulate: i) an electronic analog of the leaky integrator neural model, ii) the visual neurons of the Limulus lateral eye. This makes it possible to investigate the resonant amplification of the impulse density modulation for v 1+v 2 which approaches the free-run discharge rate; this resonance is predicted by the Volterra series representation of the leaky integrator (Poggio and Torre, 1977). The resonant responses obtained look very similar for the simulated discharge and for the experimental one.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00365767
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Use of conditional distributions in the analysis of ion channel recordings (1991)
    Springer
    European biophysics journal 20 (1991), S. 31-39 
    Details
    ISSN: 1432-1017
    Keywords: Ion channels ; Markov processes ; Conditional distributions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract A method to test the Markov nature of ion channel gating is proposed. It makes use of singly and doubly conditional distributions. The application of this method to recordings from single BK channels provides evidence that at least two states of the underlying kinetic scheme are left at a constant rate. Moreover, the probabilities, when leaving a state, of reaching another given state are shown to be constant for all the states of the system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00183277
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Coupled and uncoupled Markov systems: a possible way to distinguish between them (1992)
    Springer
    European biophysics journal 20 (1992), S. 345-353 
    Details
    ISSN: 1432-1017
    Keywords: Ion channels ; Coupled Markov systems ; Conditional distributions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract The conditional distributions of openings and closings are computed for Markov schemes with two open and two closed states and with different pathways connecting the open and closed aggregates. The computation is performed for uncoupled schemes by directly applying the probability laws and by using a convolution algorithm for coupled schemes. The results show that, for coupled schemes, conditional distributions can be nonmonotonic functions of the dwell time duration. Simulations, illustrating how the difference between coupled and uncoupled models can be detected, are also reported.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00196593
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Neural encoding in invertebrate neurons (1995)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 17 (1995), S. 725-731 
    Details
    ISSN: 0392-6737
    Keywords: General, theoretical, and mathematical biophysics (including logic of biosystems, quantum biology, and relevant aspects of thermodynamics, information theory, cybernetics, and bionics) ; Conference proceedings
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Summary The effect of a weak periodic perturbation on the firing activity of two different types of neurons is investigated. Post-stimulus and interspike interval histograms are built up from the times of occurrence of the action potentials and a comparative analysis is performed between the two preparations. A discussion of how the leaky integrate-and-fire model can mimic the experimental data is included.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02451829
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Fundamental sources of noise in sensory transduction (1995)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 17 (1995), S. 883-891 
    Details
    ISSN: 0392-6737
    Keywords: General, theoretical, and mathematical biophysics (including logic of biosystems, quantum biology, and relevant aspects of thermodynamics, information theory, cybernetics, and bionics) ; Conference proceedings
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Summary The contribution of chemical steps in trasduction chains to the output noise of a receptor cell (as opposed to the noise inherent in the stimulus,e.g., a dim light flash) has been evaluated both analytically and by a computer simulation study on a simple model, using a Monte Carlo technique. The noise deriving from chemical reactions (chemical shot noise, CSN) is shown to add to the source noise thereby increasing significantly the output variation coefficient. It is proposed that this noise contribution should be taken into account in interpreting the sensitivity of a sensory system and in particular the dose-response curves at low levels of the stimulus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02451846
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    New trends in photobiology - Photobehaviour of Halobacterium halobium: proposed models for signal transduction and motor switching
    Amsterdam : Elsevier
    Journal of Photochemistry and Photobiology B: Biology 24 (1994), S. 75-99 
    Details
    ISSN: 1011-1344
    Keywords: Bacterial rhodopsins ; Escherichia coli ; Halobacterium halobium ; Mathematical models of taxis ; Methyl-accepting proteins ; Phoborhodopsin ; Photocycle ; Photomovements ; Photoreception ; Phototaxis ; Sensory rhodopsins ; Sensory transduction
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/1011-1344(94)07009-1
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  • 9
    Electronic Resource
    Electronic Resource
    Rectification and spike synchronization in the Limulus lateral eye (1973)
    Springer
    Biological cybernetics 14 (1973), S. 155-160 
    Details
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Notes: Abstract The encoding of light stimuli into spike trains in the Limulus lateral eye is shown to be markedly nonlinear in our conditions of stimulation. Our experimental results support the conclusion that nonlinearities are enhanced by lateral inhibition but arise within the single ommatidium, and are due to the high gain in the transduction from generator potential to spike rate. This high gain is in turn related to the existence, in the steady relation between generator potential and spike rate, of a positive threshold on the generator potential.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00288917
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Spike amplitude modulation at high stimulation frequencies (1971)
    Springer
    Biological cybernetics 8 (1971), S. 47-50 
    Details
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Notes: Summary A technique of mathematical analysis has been developed for studying spike amplitude variations, during natural sinusoidal stimulation. This technique is suitable even when stimulation frequency is of the same order as, or higher than, the cell firing rate. We used this technique for the cat's retinal ganglion cells. The results agree with the previous ones (Gestri et al., 1967) at low stimulation frequencies and show that the spike amplitude modulation occur even at high frequencies, the phase shift between spike amplitude and firing probability being a function of the stimulation frequency.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00288731
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    Paper (German National Licenses)
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