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  • 1
    Electronic Resource
    Electronic Resource
    Granuloma eosinophilicum faciei – erfolgreiche kryochirurgische Behandlung bei sechs Patienten (1998)
    Springer
    Der Hautarzt 49 (1998), S. 477-481 
    Details
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Granuloma eosinophilicum faciei ; Granuloma faciale ; Kryotherapie ; Kryochirurgie ; Key words Granuloma eosinophilicum faciei ; Granuloma faciale ; Cryotherapy ; Cryosurgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Six patients with granuloma faciale, including patients with multiple lesions, were treated successfully with cryosurgery. Granuloma faciale is known to be difficult to treat. Cryosurgery is an effective and minimally invasive therapy for this granulomatous inflammation of the skin. It should be considered as an alternative to dapsone.
    Notes: Zusammenfassung Sechs Patienten mit Granuloma eosinophilicum faciei, darunter auch Patienten mit multiplen Läsionen, wurden mit Erfolg kryochirurgisch behandelt. Das Granuloma eosinophilicum faciei ist gegenüber vielen Behandlungsformen therapieresistent. Die Kryotherapie stellt eine wirksame und wenig belastende Behandlung für diese granulomatöse Entzündung dar. Sie sollte als Therapiealternative gegenüber einer systemischen Behandlung mit Dapson erwogen werden.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001050050773
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The GABAA receptor antagonist picrotoxin attenuates most sleep changes induced by progesterone (1999)
    Springer
    Psychopharmacology 141 (1999), S. 213-219 
    Details
    ISSN: 1432-2072
    Keywords: Key words Neurosteroids ; GABAA receptor ; Sleep ; EEG spectral analysis ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Progesterone has been shown to exert benzodiazepine-like effects on sleep, which suggests that they are mediated by an agonistic modulation of GABAA receptor functioning. To assess the involvement of GABAA receptors, we investigated the sleep responses to one dose of the GABAA antagonist picrotoxin (1.5 mg/kg) and progesterone (90 mg/kg), administered IP to eight rats alone and in combination, during the first 4 post-injection hours. Compared with vehicle, picrotoxin significantly delayed the latency to non-rapid eye movement sleep (non-REMS) and thereby decreased all sleep states, but barely affected the EEG activity within non-REMS. Progesterone significantly shortened non-REMS latency, increased pre-REMS, depressed low-frequency EEG activity (≤8 Hz) and augmented EEG activity in the higher frequencies within non-REMS. Except for the changes in high-frequency EEG activity, picrotoxin attenuated all effects of progesterone. These findings support the notion that GABAA receptors play an important role in the sleep effects of progesterone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002130050827
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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