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  • 1
    Electronic Resource
    Electronic Resource
    Isolation and partial characterization of crystal matrix protein as a potent inhibitor of calcium oxalate crystal aggregation: evidence of activation peptide of human prothrombin (1994)
    Springer
    Urological research 22 (1994), S. 45-50 
    Details
    ISSN: 1434-0879
    Keywords: Calcium oxalate crystal ; Crystal matrix protein ; Crystal aggregation ; Aggregation inhibitor ; Human prothrombin ; Activation peptide (fragment 1+2)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In order to clarify the characteristics of crystal matrix protein (CMP), which exhibits a remarkable affinity for calcium oxalate crystals and may be important in stone pathogenesis, we have isolated CMP from macromolecular matrix substances of newly-formed calcium oxalate crystals. Purification of CMP consisted of calcium oxalate crystal formation, dissolution of crystals, electrodialysis, anion exchange chromatography and high-performance liquid chromatography. CMP showed the protein band of 31 kDa in sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The N-terminal amino acid sequence of CMP was identical to that of human prothrombin. Both anti-CMP polyclonal antibody and antihuman prothrombin antibody cross-reacted well with human prothrombin and CMP in Western blotting. Its amino acid composition and its molecular weight of 31 kDa strongly suggest that CMP is the activation peptide of human prothrombin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00431548
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Finite element methods for constrained problems in elasticity (1982)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 18 (1982), S. 701-725 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Several different variational formulations of boundary-value problems with constraints are discussed, with particular reference to constrained problems in elasticity. Special attention is given to exterior penalty methods. A discussion of the conditions necessary for penalty methods to provide a basis for stable and convergent finite element methods is given. In particular, the use of reduced integration is discussed and criteria on the order of reduced integration rules sufficient to produce stable and convergent schemes are described. Applications of reduced integration-penalty methods to incompressible elasticity problems and contact problems are described.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620180507
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Analysis of global expansion methods: Weakly asymptotically diagnonal systems, L.M. Delves et al., Academic Press, London, July 1981. No. of pages: X + 276. Price: £20.40 ($49.00). ISBN 0.12.208880.8 (1982)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 18 (1982), S. 165-165 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620180115
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    APPLICATION OF TOPOLOGICAL OPTIMIZATION TECHNIQUES TO STRUCTURAL CRASHWORTHINESS (1996)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 39 (1996), S. 1383-1403 
    Details
    ISSN: 0029-5981
    Keywords: crashworthiness ; homogenization ; topology design ; automotive structure optimization ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The topological optimization of components to maximize crash energy absorption for a given volume is considered. The crash analysis is performed using a DYNA3D finite element analysis. The original solid elements are replaced by ones with holes, the hole size being characterized by a so-called density (measure of the reduced volume). A homogenization method is used to find elastic moduli as a function of this density. Simpler approximations were developed to find plastic moduli and yield stress as functions of density.Optimality criteria were derived from an optimization statement using densities as the design variables. A resizing algorithm was constructed so that the optimality criteria are approximately satisfied. A novel feature is the introduction of an objective function based on strain energies weighted at specified times. Each different choice of weighting factors leads to a different structure, allowing a range of design possibilities to be explored.The method was applied to an automotive body rear rail. The original design and a new design of equal volume with holes were compared for energy absorption.
    Additional Material: 25 Ill.
    Type of Medium: Electronic Resource
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    Paper (German National Licenses)
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