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  • 1
    Electronic Resource
    Electronic Resource
    A phase II trial of gallium nitrate (NSC #15200) in advanced or recurrent squamous cell carcinoma of the cervix (1991)
    Springer
    Investigational new drugs 9 (1991), S. 109-111 
    Details
    ISSN: 1573-0646
    Keywords: gallium nitrate ; advanced or recurrent squamous carcinoma ; cervix
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Twenty-four evaluable patients with advanced, persistent or recurrent squamous cell carcinoma of the cervix were treated with 750 mg/m2 of gallium nitrate (NCS # 15200) every three weeks. No patient had prior cytotoxic chemotherapy. Two patients had a partial response (8.3%), ten patients had stable disease (41.7%), and twelve (50%) had increasing disease. The 95% upper confidence bound for response is 24.0%. The major toxicities were nausea, vomiting and anemia. Gallium nitrate has minimal activity in patients with previously untreated squamous cell carcinoma of the cervix.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00194560
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Phase II evaluation of dianhydrogalactitol in the treatment of advanced non-squamous cervical carcinoma (1984)
    Springer
    Investigational new drugs 2 (1984), S. 331-333 
    Details
    ISSN: 1573-0646
    Keywords: galactitol ; dianhydrogalactitol ; cervix ; non-squamous-chemotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary In an on-going Phase II evaluation, dianhydrogalactitol (NSC 132313) was administered intravenously to 28 patients with advanced or recurrent non-squamous cell carcinoma of the cervix. The initial dosage was 60 mg/m2/wk with escalation to 75 mg/m2/wk if there were no adverse effects. Twenty-seven patients were evaluable for toxicity and response. There was one complete response and one partial response. Adverse effects were not infrequent but tolerable.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00175387
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Voltammetry and LCEC of isoflavones (1997)
    Weinheim : Wiley-Blackwell
    Electroanalysis 9 (1997), S. 796-799 
    Details
    ISSN: 1040-0397
    Keywords: Isoflavones ; Cyclic voltammetry ; High-performance liquid chromatography ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: This study provides electrochemical and LCEC determination for three of the most abundant and most important isoflavones, Biochanin A, formononetin, and genistein. Cyclic voltammetry and pH-potential diagrams show that the isoflavones undergo pH-dependent irreversible oxidations. The LCEC determination of the isoflavones has been optimized for mobile phase composition and detection potential. Sub-nanogram detection limits have been achieved.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/elan.1140091013
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Electrochemistry of hexacoordinate silicon(IV) porphyrin complexes (1997)
    Weinheim : Wiley-Blackwell
    Electroanalysis 9 (1997), S. 1273-1277 
    Details
    ISSN: 1040-0397
    Keywords: Cyclic voltammetry ; Porphyrins ; Silicon ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Cyclic voltammetry was used to characterize the oxidation-reduction behavior of a series of novel hexacoordinate silicon(IV) porphyrin complexes. Each (Por)SiX2 [Por = the dianions of the porphyrins: tetrakis(p-tolyl)porphyrin (TTP), tetraphenylporphyrin (TPP), tetrakis(p-trifluoromethylphenyl)porphyrin (TTFP), octaethylporphyrin (OEP), × = F, Cl, O3SCF3] complex undergoes one to two oxidations and one to two reductions, all occurring at the porphyrin ring. No silicon(IV) reduction is observed for any of the porphyrin complexes. The effects of solvent, supporting electrolyte, substituents on the porphyrin ring, axial ligands, certral metal, and ruffling of the porphyrin ring are described.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/elan.1140091611
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    Paper (German National Licenses)
    Fulltext
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