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  • 1
    Electronic Resource
    Electronic Resource
    Ooplasmic segregation in theTubifex egg: Mode of pole plasm accumulation and possible involvement of microfilaments (1982)
    Springer
    Development genes and evolution 191 (1982), S. 246-256 
    Details
    ISSN: 1432-041X
    Keywords: Tubifex egg ; Ooplasmic segregation ; Pole plasm ; Microfilaments ; Cytochalasin B
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Ooplasmic segregation, i.e. the accumulation of pole plasm in theTubifex egg, consists of two steps: (1) Cytoplasm devoid of yolk granules and lipid droplets migrates toward the egg periphery and forms a continuous subcortical layer around the whole egg; (2) the subcortical cytoplasm moves along the surface toward the animal pole in the animal hemisphere and toward the vegetal pole in the vegetal hemisphere, and finally accumulates at both poles of the egg to form the animal and vegetal pole plasms. Whereas the subcortical layer increases in volume during the first step, it decreases during the second step. This is ascribed to the compact rearrangement in the subcortical layer of membraneous organelles such as endoplasmic reticulum and mitochondria. The number of membraneous organelles associated with the cortical layer increases during the second step. Electron microscopy reveals the presence of microfilaments not only in the cortical layer but also in the subcortical layer. Subcortical microfilaments link membraneous organelles to form networks; some are associated with bundles of cortical microfilaments. The thickness of the cortical layer differs regionally. The pattern of this difference does not change during the second step. On the other hand, the subcortical cytoplasm moves ahead of the ‘stationary’ cortical layer. The accumulation of pole plasm is blocked by cytochalasin B but not by colchicine. The first step of this process is less sensitive to cytochalasin B than the second step, suggesting that these two steps are controlled by differnt mechanisms. The mechanical aspects of ooplasmic segregation in theTubifex egg are discussed in the light of the present observations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00848412
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  • 2
    Electronic Resource
    Electronic Resource
    Kabuki make-up syndrome and report of a case with hydrocephalus (1998)
    Springer
    Child's nervous system 14 (1998), S. 230-235 
    Details
    ISSN: 1433-0350
    Keywords: Key words Aqueductal stenosis ; Hydrocephalus ; Kabuki make-up syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a 22-year-old man with hydrocephalus caused by aqueductal stenosis. The patient was diagnosed with Kabuki make-up syndrome based on associated findings such as a peculiar facies, postnatal growth deficiency, brachydactyly of the fifth fingers, undescended testes, and malrotation of the colon. Kabuki make-up syndrome, recognized in Japan in 1981, is characterized by five cardinal manifestations: a peculiar facies, skeletal anomalies, dermatoglyphic anomalies, slight to moderate mental retardation, and postnatal dwarfism. Neurological anomalies have been reported to include neonatal hypotonia, feeding problems, seizures, West syndrome, microcephaly, brain atrophy, GH deficiency, precocious puberty, delayed sexual development, and diabetes insipidus. Aqueductal stenosis may be caused by part of the series of midline anomalies. Physicians should pay attention to associated anomalous characteristics suggesting a malformation syndrome when they encounter nontumoral aqueductal stenosis in adolescents or adults.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003810050218
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    Paper (German National Licenses)
    Fulltext
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