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  • density fluctuation  (2)
  • DNA damage  (1)
  • Epstein-Barr virus  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Urinary excretion of mutagens and covalent DNA damage induced in the bladder and kidney after passive smoking in rats (1994)
    Springer
    Urological research 22 (1994), S. 93-97 
    Details
    ISSN: 1434-0879
    Keywords: Passive smoking ; DNA damage ; Bladder ; Kidney ; 32P-postlabeling assay ; Urine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Using 32P-postlabeling assay, we studied the effect of sidestream smoke of cigarettes, so-called passive smoking, on the covalent DNA adduct formation in an animal model. Urine samples of 18 rats, 9 male and 9 female, before smoking resulted in an average of 2.4 adducts per 1×107 nucleotides per 24-h urine of a rat in the target plasmid DNA after incubation for 2 h in vitro. Urine samples of 4 out of 6 rats after exposure to sidestream smoke induced additional adducts in the target DNA. The incidence increased to 17.5 adducts per 1×107 nucleotides per 24-h urine of a rat. Without exposure to smoke, no increase in the adduct formation was observed. Adduct formations similar to those induced in vitro were detected in the bladder and kidney DNA, but not in the testicular DNA, of the four rats exposed to sidestream smoke. These observations suggest that passive smoking causes covalent DNA damage of the cells in the bladder and kidney by excreting chemicals in urine. Passive smoking as well as active smoking might contribute to the bladder and renal carcinogenic process.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00310998
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Enhanced expression of Epstein-Barr virus early antigens by antitubulin agents in a latently infected human lymphoblastoid cell line (1985)
    Springer
    Cellular and molecular life sciences 41 (1985), S. 372-373 
    Details
    ISSN: 1420-9071
    Keywords: Epstein-Barr virus ; tumor promoter ; antitubulin agents ; vinblastine ; vincristine ; anticancer agents
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 28 anticancer agents have been surveyed for Epstein-Barr virus (EBV) activating potency. Two vinca alkaloids with antitubulin activity, vinblastine (VLB) and vincristine (VCR), enhanced the expression of EBV early antigens (EA) in a latently infected human lymphoblastoid cell line (Raji), when used in combination withn-butyrate. Other antitubulin agents, colchicine, colcemid, and podophyllotoxin, had the same effect, although their effects were less than that of the potent tumor promoter, 12-O-tetradecanoyl phorbol-13-acetate (TPA).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02004511
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    HCN laser scattering on the JIPP T-IIU tokamak (1988)
    Springer
    International journal of infrared and millimeter waves 9 (1988), S. 655-665 
    Details
    ISSN: 1572-9559
    Keywords: HCN laser scattering ; density fluctuation ; tokamak plasma ; ICRF heating
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A 4-channel HCN laser scattering system has been developed and applied to the JIPP T-IIU tokamak. Main aim of this system is to study microturbulence excited in the plasma, especially in the high power ICRF heating experiment. The observed density fluctuations are in a frequency range of the electron diamagnetic drift wave and have broad frequency spectra. The main part of the wavenumber is found to satisfy the condition of $$k_ \bot \rho _i \lesssim 1$$ . In the heating experiments, deterioration of the energy confinement time is observed, and the density fluctuation level increases with the increase of the heating power.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01013418
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  • 4
    Electronic Resource
    Electronic Resource
    Measurement of density fluctuations on the JIPP T-IIU tokamak via an HCN laser scattering (1985)
    Springer
    International journal of infrared and millimeter waves 6 (1985), S. 729-739 
    Details
    ISSN: 1572-9559
    Keywords: HCN laser scattering ; density fluctuation ; tokamak plasma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Observation of density fluctuations in tokamak plasmas is important to study the plasma confinement and to perform high power heating of the plasma. We observed the density fluctuations by means of an HCN laser scattering method during rf heating in the ion-cyclotron range of frequency on a tokamak plasma. The density fluctuations at the drift wave frequency are not enhanced so much by the heating, but the frequency spectrum is shifted to higher frequency. The increase of the density fluctuation level during the heating has been observed only in low-frequency region owing to MHD activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01011949
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    Paper (German National Licenses)
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