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  • lipid peroxidation  (2)
  • Defects  (1)
  • Oligonucleotide derivatives  (1)
  • histochrome
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of superconductivity 6 (1993), S. 317-320 
    ISSN: 1572-9605
    Keywords: Defects ; substrate ; orientation ; heteroepitaxy ; twinning
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
    Notes: Abstract The lattice mismatch and stereographic maps of the prevailing epitaxial relationships for HTS on perovskite-type substrates have been determined as a function of substrate orientation. The compositions and orientations of substrates for creating perfect single crystalline HTS layers are presented. The misfit may be decreased to nearly 0 for LnGaO3 and SrLnGaO4, where Ln is a rare-earth ion having a large ionic radius, by optimal choice of substrate orientation. For the LnAlO3 and (Ca, Sr)LnAlO4 families, good lattice match is lacking. The best compounds among them are LaAlO3 and SrLaAlO4. Because of the weak orientation dependence of the misfit for SrTiO3 and the LnAlO3 family, the main purpose of substrate orientation optimization is to suppress polysynthetic twinning.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of experimental biology and medicine 122 (1996), S. 1222-1224 
    ISSN: 1573-8221
    Keywords: free-radical pathology ; antioxidants ; polyhydroxynaphthoquinones ; histochrome ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract A method for measuring the plasma concentration of histochrome is described. Echinochrome, a naturally occurring polyhydroxynaphthoquinone with antioxidant and cardioprotective activities, is the active ingredient of histochrome. Plasma histochrome concentration is measured in patients with acute myocardial infarction. This method can be used for pharmacokinetic analysis.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of experimental biology and medicine 117 (1994), S. 474-475 
    ISSN: 1573-8221
    Keywords: lipid peroxidation ; diene conjugates ; malonic dialdehyde ; antioxidant activity ; vitamin E
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract An increase in the content of primary and final lipid peroxidation (LPO) products and a decrease in the fat- and water-soluble antioxidants in blood plasma are revealed in a study of hypohydration induced by administration of 40 mg furosemide alone or in combination with 1 tablet of triampure. Intensification of free radical processes in states simulating weightlessness may be related to the loss of fluid due to transformation of water-electrolyte metabolism.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1573-8221
    Keywords: human heart ; age ; ischemia ; lipid peroxidation ; antiradical activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Levels of lipoperoxides and hydrophobic scavengers of free radicals were estimated in n-hexane extracts of myocardial biopsy specimens taken from cardiac patients (children and adults) during surgical operations. Ultraviolet spectra of these extracts were found to contain four absorption bands with peaks at 214, 233, 258, and 298 nm that characterize the levels of diene and triene conjugates. A comparison of the data obtained for children and adults suggested that the total antiradical activity of the cardiac muscle decreases while its content of vitamin E remains virtually unchanged during ontogeny. Significantly reduced vitamin E levels were noted in specimens from patients with chronic ischemic heart disease.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0952-3499
    Keywords: Sequence-specific photomodification ; Oligonucleotide derivatives ; Ethidium ; Azidoethidium ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Oligodeoxyribonucleotide derivatives containing ethidium or azidoethidium residues attached to 3′ and/or 5′ end were prepared. These derivatives formed tight specific complexes with complementary oligodeoxyribonucleotides where each attached ethidium residue led to an increase of complex Tm by 20-30°C. Tandem complexes of two oligodeoxyribonucleotides containing ethidium residues with an oligodeoxyribonucleotide having two adjacent complementary sequences for these Oligonucleotide were investigated. Photoinduced reactions of a number of ethidium and azidoethidium oligodeoxyribonucleotide derivatives with target complementary single-stranded and double-stranded oligo- and polydeoxyribonucleotides were investigated. The irradiation led to direct photocleavage of the target oligo- or polynucleotide, to formation of hidden (piperidine cleavable) modifications of the target of formation of covalent adducts between ethidium oligodeoxyribonucleotide derivative and the target. In a number of experiments, azidoethidium dyes were demonstrated to be considerably stronger photosensitizers than ethidium ones. Depending on the nature of the target (single- or double-stranded DNA) and on the irradiation conditions, the total damages to the target oligo- or polydeoxyribonucleotides ranged from 10-70% (for ethidium dyes) to 30-80% (for azidoethidium dyes).
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
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