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  • 1
    ISSN: 1437-160X
    Keywords: Key words Interstitial pneumonia ; KL-6 ; Corticosteroids ; Marker
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The objective of this study was to determine the role of serum KL-6 levels as a marker for the activity of interstitial pneumonia in patients with connective tissue diseases. The serum concentrations of KL-6, a glycoprotein produced mainly by pulmonary type II epithelial cells, were measured in 21 patients with connective tissue disease. The activity of interstitial pneumonia was compared with the associated serum KL-6 concentrations. Serum KL-6 concentrations in patients with interstitial pneumonia were significantly higher than those in the controls. Among patients with active interstitial pneumonia, serum KL-6 concentrations following the treatment (after improvement) were significantly lower than the pretreatment values. The extent of the pulmonary fibrosis correlated positively with the serum KL-6 concentrations during the inactive phase of the interstitial pneumonia. These results suggest that sequential measurement of serum KL-6 levels is a new and useful means for the evaluation of interstitial pneumonia in patients with connective tissue diseases.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of plastic surgery 20 (1997), S. 127-131 
    ISSN: 1435-0130
    Keywords: Electrical burns ; Progressive necrosis ; Delayed bleeding ; Arterial injury ; Pathology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This study describes the histologic findings of injured arteries after electrical burns. These findings are shown to correlate with the clinical findings of soft tissue necrosis and delayed bleeding. Eight patients with severe electrical injuries who underwent amputations of extremities were studied. Thickening of the tunica intima and degeneration of the tunica media, associated with small artery occlusion, were evident in the arteries at the transition zone between severely injured and grossly normal areas.
    Type of Medium: Electronic Resource
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