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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 72 (1987), S. 402-405 
    ISSN: 1432-0533
    Keywords: Myelin ; Effects of radiation ; Spinal cord ; Tritium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of a selective irradiation of myelin by3H β-particles was studied by light and electron microscopic methods in guinea pig spinal cord. The animals were injected with [3H]leucine shortly after birth when the rate of myelin biosynthesis is high and sacrificed 130 days later. In spinal cord the radioactivity was mainly preserved in myelin because the half life of myelin proteins is much higher than that of most other CNS protein. As a consequence the irradiation dose in the white matter was much higher than in the gray matter. In myelin internally irradiated by3H β-particles within 130 days at a dose of 10 Gy no alterations could be detected either by morphological or by morphometric methods.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 347 (1978), S. 449-456 
    ISSN: 1435-2451
    Keywords: Prospective trial ; Surgery, results of ; Prospektive Studie ; Ergebnisse in der Chirurgie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Seit der Erstbeschreibung einer prospektiven klinischen Untersuchung durch J. Lind (1753) ist die kontrollierte Studie zum wichtigen Gegenstand klinischer Forschung geworden. Gegenstände von prospektiven Studien können sein : prophylaktische Maßnahmen zur Verhütung von Komplikationen (z. B. Thrombose, Streßulcus, Hepatitis, Wundinfektion), Operationsindikation, Operationsvorbehandlung, Operationstaktik und -technik sowie die Nachbehandlung. Für jede Fragestellung werden Beispiele angeführt.
    Notes: Summary Since the first clinical prospective trial of J. Lind in 1753, the controlled study has proved to be an essential instrument in clinical research. Possible topics include: pharmacologic prophylaxis of complications such as stress ulcer, thrombosis, etc., indications for operation, preoperative preparation, choice of surgical procedure, and techniques or postoperative treatment. Examples for each topic are given.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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