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  • Eighth nerve  (2)
  • Histopathology of Ménière's disease  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 224 (1979), S. 17-23 
    ISSN: 1434-4726
    Keywords: Eighth nerve ; Inner ear ; Human ; Fluorescence microscopy ; Electron microscopy ; Menière ; Neurilemoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fluorescence microscopy was used to examine the adrenergic, bloodvessel-independent innervation of the 8th nerve and inner ear specimens in patients with otoneurological diseases. Specifically fluorescent adrenergic axons were scantily seen among the myelinated nerve fibers in the 8th nerve and in the subepithelial regions of the end organs but not in the endolymphatic sac.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 215 (1977), S. 45-54 
    ISSN: 1434-4726
    Keywords: Vestibular nerve morphology ; Histopathology of Ménière's disease ; Ménière's disease ; Vestibular nerve pathology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The morphology of the vestibular nerve was studied in three fresh nerve specimens obtained by surgery from two patients with Ménière's disease and one patient with tinnitus after an attack of sudden deafness. The number of nerve fibres appeared light microscopically normal. The vestibular ganglion cells of the Ménière-specimens showed, as a characteristic finding advanced vesiculation of the cytoplasm. This change was confirmed by electron microscopy and the vacuoles appeared to consist of widened endoplasmic reticulum cisternae. Numerous primary lysosomes and lipofuscin granules were observed in all vestibular ganglion cells but their number appeared increased in the specimens from Ménière-patients. Some of the vestibular ganglion cells of these patients showed a filamentous appearance and the number of glycogen granules seemed reduced in all of them. All vestibular ganglion cells observed were unmyelinated. The degenerative changes observed might explain the typical elevation of the threshold for vestibular stimulation in Ménière's disease.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 230 (1981), S. 161-170 
    ISSN: 1434-4726
    Keywords: Sudden deafness ; Vertigo ; Neurectomy ; Eighth nerve ; Light microscopy ; Electron microscopy ; Demyelinating disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A patient initially presenting typical symptoms of idiopathic sudden deafness later developed disabling episodic vertigo, which led to translabyrinthine eighth nerve transection. Morphological examination of the removed cochlear nerve specimen revealed a demyelinating process in the neuroglial portion of the nerve. The major part of the peripheral, neurolemmal portion of the cochlear nerve was normal. The inferior vestibular nerve was fibrotic. The major part of the superior vestibular nerve was normal. Some of its peripheral bundles showed increased endoneurial fibrosis. It is suggested that a demyelinating process was the cause of the patient's symptoms.
    Type of Medium: Electronic Resource
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