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  • 1
    ISSN: 1432-0533
    Keywords: Key words Central nervous system endothelial ; lipopigment ; Equine motor neuron disease ; Equine ; degenerative myeloencephalopathy ; Vitamin E ; deficiency
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two spontaneous neurodegenerative diseases of the horse, equine motor neuron disease (EMND) and equine degenerative myeloencephalopathy (EDM), have been associated with α-tocopherol deficiency, and both were characterized by prominent accumulations of endothelial lipopigment in the small vessels of the spinal cord. These endothelial pigment deposits appear to be reversible. In EMND horses pasture-supplemented for 9 months or more after the progression of weakness and wasting had arrested, there was very little endothelial lipopigment. The origin and the potential effects of these endothelial lipopigment accumulations are discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 178 (1988), S. 389-397 
    ISSN: 1432-0568
    Keywords: Guinea-pig ; Trachea ; Airway ; Smooth muscle ; Cartilage ; Elastic fibres ; Collagen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The trachea of the guinea-pig measures about 47.5 mm in situ, and it shrinks to 38 mm when excised. It can be stretched to the in situ length with a load of 2–4 grams. The transverse area of its lumen measures about 4.5 mm2 in the cervical portion, whereas in the lowermost thoracic portion it measures 2.8 mm2, a difference of 37%. The lumen has an oval shape with the transverse diameter always exceeding the sagittal diameter. The separation between the ends of a cartilage in the dorsal region of the trachea is greater in the cervical than in the thoracic region. Elastic fibres are abundant in the tunica propria and run longitudinally; the collagen is in some areas arranged with a criss-cross pattern. The muscle is inserted on the concave aspect of each cartilage at some distance from the ends of the cartilage and it is therefore much longer than the gap between cartilage ends. Upon contraction in vitro (induced by carbachol) the muscle shortens by about 50%; there is a marked decrease of the transverse diameter of the trachea, and a certain decrease also of the sagittal diameter due to a straightening of the muscle and a change in shape and a movement of the mucosa. The cartilage ends are brought together and in the thoracic region they are bent and overlap extensively. The lumen of the trachea becomes circular and its area is reduced to 2.2 mm2 in the cervical portion and 1.7 mm2 in the thoracic portion.
    Type of Medium: Electronic Resource
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