ISSN:
1432-0533
Keywords:
Progressive supranuclear palsy
;
Neurofibrillary tangles
;
Electron microscopy
;
Straight filaments
;
Twisted tubules
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The fine structure of subcortical neurofibrillary tangles was investigated in pallidum, substantia nigra, periaqueductal gray, pontine reticular gray, and dentate nucleus of 5 autopsy cases of Progressive Supranuclear Palsy. Only tangles due to straight 150 Å wide filaments have been detected. These findings, obtained from a large series of cases and areas examined, confirm previous observations on the fine structure of neurofibrillary tangles in Progressive Supranuclear Palsy and suggest that the association between tangles due to straight filaments and tangles due to twisted tubules, so far described in one case, is probably exceptional.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00691893
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