Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Strukturwandlungen der Adenomyosis uteri und der Endometriosis externa unter dem Einfluß zugeführter Hormone (1975)
    Springer
    Virchows Archiv 367 (1975), S. 241-254 
    Details
    ISSN: 1432-2307
    Keywords: Endometriosis ; Adenomyosis ; Endometrial function ; Correlation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Hormontherapie der Adenomyose und Endometriose läßt die Beurteilungsmöglichkeit des Heilungserfolges bzw. der Heilungschancen aus dem Funktionszustand des Corpusendometrium wünschenswert erscheinen. Bei systematischer korrelierender Untersuchung von Endometrium, Adenomyose und/oder Endometriose unter dem Einfluß endogener und exogener hormoneller Stimulation ergaben sich je nach Lokalisation des ektopischen Endometrium und nach Art des hormonellen Stimulus in Zeitpunkt und Ausmaß unterschiedliche Abweichungen vom Funktionszustand des Corpusendometrium. Diese lassen sich jedoch mit genügender Sicherheit jeweils voraussagen. Die hormonelle Stimulierung der Adenomyose war der des Corpusendometrium am ähnlichsten, die Endometriose des Ovars zeigte oft, insbesondere unter Gestagenreizen, eine überschießende Stimulation, während die übrigen extrauterinen Endometriosherde nur sehr schwach auf hormonelle Reize reagierten. Aus den Ergebnissen lassen sich für die Therapie wichtige prognostische Konsequenzen ableiten.
    Notes: Summary This study was undertaken to determine whether the hormonal sensitivity of the endometrium might be a measure of the effectiveness of hormonal therapy for adenomyosis and endometriosis. Accordingly, the effects of endogenous and exogenous hormones on the endometrium, adenomyosis, and endometriosis were correlated. The results revealed that, depending on where the ectopic endometrial tissue was located and on the type (duration and intensity) of hormonal treatment, the functional response of the endometriosis varied from that of the endometrium. The variations, however, can be predicted. The response of adenomyosis to hormonal stimulation was most like that of the endometrium. Endometriosis of the ovary often revealed an excessive response to stimulation, especially after gestagens. The other types of extrauterine foci of endometriosis, however, reacted only weakly to hormonal therapy. Important prognostic consequence for therapy can be drawn from the results.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00430711
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Immunohistological and histochemical localization of relaxin in the metrial gland of the pregnant ratThis work has been supported by the aid of United States Public Health Service grant GM-10210. (1965)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 117 (1965), S. 433-450 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The presence of relaxin in uteri, placentae, and ovaries of pregnant rats was studied immunohistologically with fluorescein labeled anti-relaxin serum and confirmed by histological and histochemical techniques.In sections of uteri from day 12 of pregnancy stained with these antisera, the cytoplasm of the granular cells of the mesometrial decidua gave off a yellow-green fluorescence indicating antirelaxin binding. On day 15, 17 and 19, the granular cells of the metrial gland and occasional lakes in near-by vascular lumina fluoresced. No other specific fluorescence was evident in the uteri or placentae. The fluorescent regions of these cells corresponded exactly with the cytoplasmic aggregates of granules in the metrial gland and mesometrial decidua. Histochemical studies of these granules which bound with antirelaxin, revealed a chemical composition congruent with that known for relaxin, and with that of the relaxin-containing granules of human decidual and placental cells. The dissolution of connective tissue fibers, believed to be a main function of relaxin, was observed in the last days of pregnancy within the metrial gland, especially where it borders the mesometrial decidua. These results correlate well with Schaub's discovery of a collagen-degrading substance in the metrial gland. Other actions of relaxin may be explained as secondary to the primary effect of dissolution of collagen. The relaxin-containing cells in the human and in the rat differ only in their localization in the tissue which depends on their phylogenetic adaptation to different placentational needs. The metrial gland cells of the pregnant rat correspond in their function to the basal trophoblastic cells of the human term placenta. The non-menstruating rat has no counterpart for the endometrial granulocytes, but the granular cells in the mesometrial decidua adjacent to the site of implantation correspond to the endometrial granular cells surrounding the implantation site in the human; it is suggested their collagen dissolving action facilitates implantation.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001170308
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Morphological and histochemical observations on trophoblast and decidua of the basal plate of the human placenta at termThis work has been supported by the aid of the United States Public Health Service, Grant GM-09472-02. (1964)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 115 (1964), S. 309-326 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The trophoblastic cells of the basal plate at the end of pregnancy still have an important hormonal function, in contrast to the decidual cells which appear to exert their main function at the onset of pregnancy. Possibly the decidual cells are functionally replaced by the basal trophoblastic cells, which phagocytize and destroy them. Although both types of cells are structurally quite similar and appear to produce the same hormones, but at different times, genetically they are very different. They degenerate morphologically in much the same way, but the cause for the retrogressive change for each is distinct. The trophoblastic cells degenerate with reticulum-fibrinoid inclusions which they have mainly phagocytized. The decidual cells perish with collagen inclusions formed from collagen fibers they in turn produced.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001150207
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    The effect of relaxin on the endometrium of monkeys histological and histochemical studiesThis work has been supported by U.S.P.H.S. grants HD 00422 and GM 10210. (1966)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 119 (1966), S. 61-77 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Castrated or juvenile monkeys were given estrogen, progesterone and relaxin in various doses and combinations. Relaxin induced: (1) a dilatation of the superficial endometrial blood vessels and proliferation of their endothelial cells; this effect may be regarded as due to relaxin alone; (2) an intensified differentiation of the endometrial stroma cells into predecidual cells and granulocytes, dependent on estrogen priming and the simultaneous injection of progesterone; (3) a periarteriolar mantle-like accumulation of granulocytes in the basal endometrium dependent on the above pretreatment; (4) a degranulation of the granulocytes and hypersegmentation of their nuclei following prolonged administration of relaxin with estrogen and progesterone. Morphologically and histochemically the granulocytes of the monkey are almost identical with those of the human uterus and with the granular cells in the decidua and mesometrial gland of the pregnant rat. Immunohistologically relaxin has been demonstrated in the granulocytes of man and rat. The changes in the arterioles brought about by exogenous relaxin occur under physiological conditions only with the increased formation of endogenous relaxin during early pregnancy. They have been described in the immediate vicinity of ovum implantation in man, monkey, and rat. Their function possibly lies in the preparation of blood spaces for nutrition of the young embryo.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001190105
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...