ISSN:
1432-0533
Keywords:
Labelled Penicillin
;
Quantitative Radioautography
;
Epileptogenous Foci
;
Blood Brain Barrier
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The intracerebral diffusion of penicillin, intravenously injected to stimulate epileptogenic foci in the cat, has been studied by means of radioautography. Two facts are pointed out: First, penicillin is located in the lesion and its vicinity but nowhere else in the brain. The antibiotic seems to be stored in the focus from which it will spread into the nervous tissue. Second, the spread of penicillin is slightly increased when the time of contact of penicillin with the living brain is longer. Thus, the focus and its surroundings are the only regions concerned by penicillinic activation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00685587
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