ISSN:
1432-1041
Schlagwort(e):
Lithium salts
;
gastrointestinal absorption
;
plasma and intracellular kinetics
;
affective disorders
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
,
Medizin
Notizen:
Summary Five healthy volunteers were treated orally with lithium carbonate, sulphate, or chloride. There were no significant differences in area under time-concentration curves, half-lives, total body clearance or apparent distribution volumes between the various salts, either in plasma or in the RBC compartment. The carbonate salt did show a higher RBC/plasma distribution ratio than the other salts, which might possibly imply greater therapeutic effectiveness of this salt. Some considerations on the tolerability of various lithium salts are discussed.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00561406
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