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  • 1
    Electronic Resource
    Electronic Resource
    Determination of monosaccharides and sugar alcoholsin tissues from diabetic rats by high-performance liquid chromatography with pulsed amperometric detection
    Amsterdam : Elsevier
    Analytical Biochemistry 206 (1992), S. 98-104 
    Details
    ISSN: 0003-2697
    Keywords: [abr] HPAEC; high-performance anion-exchangechromatography ; [abr] PAD; pulsed amperometoric detection ; [abr] PED; pulsed electrochemical detector
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0003-2697(05)80016-8
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Determination of monosaccharides and sugar alcoholsin tissues from diabetic rats by high-performance liquid chromatography with pulsed amperometric detection
    Amsterdam : Elsevier
    Analytical Biochemistry 206 (1992), S. 98-104 
    Details
    ISSN: 0003-2697
    Keywords: [abr] HPAEC; high-performance anion-exchangechromatography ; [abr] PAD; pulsed amperometoric detection ; [abr] PED; pulsed electrochemical detector
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0003-2697(05)80016-8
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    HepG2/erythrocyte glucose transporter (GLUT1) gene in NIDDM: a population association study and molecular scanning in Japanese subjects (1995)
    Springer
    Diabetologia 38 (1995), S. 942-947 
    Details
    ISSN: 1432-0428
    Keywords: Key words Non-insulin-dependent diabetes mellitus ; genetics ; GLUT1 ; single-strand conformation polymorphism ; mutation.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To evaluate the role of mutations in the glucose transporter (GLUT1) gene in Japanese patients with non-insulin-dependent diabetes mellitus (NIDDM), we first conducted a population association study using the XbaI polymorphism of the gene. A polymerase chain reaction (PCR)-based assay was developed and used for the analysis. When analysed in 91 diabetic patients and 87 non-diabetic control subjects, the distribution of the genotype frequency was significantly different between the two groups (p = 0.0025). The (−) allele was significantly associated with NIDDM (odds ratio 2.317, 95 % confidence interval 1.425–3.768). To identify possible mutation(s) in the GLUT1 gene, which was in linkage disequilibrium with the (−) allele, all ten exons of the gene were analysed by PCR single-strand conformation polymorphism (SSCP) analysis in 53 diabetic patients with at least one (−) allele. Variant SSCP patterns were detected in exons 2, 4, 5, 7, 9 and 10. Sequence analysis revealed that all the variants represented silent mutations. One of the variants in exon 2, GCT (Ala15) → GCC(Ala), created a HaeIII restriction site. This polymorphism was common in Japanese subjects with heterozygosity of 0.36 and polymorphism information content 0.29. We conclude that the structural mutation of GLUT1 is rare and not likely to be a major genetic determinant of NIDDM in Japanese subjects. The XbaI (−) allele of the GLUT1 gene appeared to be a genetic marker of NIDDM in Japanese subjects. The possibility of the presence of mutation(s) in the regulatory region of the gene or in another locus nearby could not be excluded. [Diabetologia (1995) 38: 942–947]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00400583
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    HepG2/erythrocyte glucose transporter (GLUT1) gene in NIDDM: a population association study and molecular scanning in Japanese subjects (1995)
    Springer
    Diabetologia 38 (1995), S. 942-947 
    Details
    ISSN: 1432-0428
    Keywords: Non-insulin-dependent diabetes mellitus ; genetics ; GLUT1 ; single-strand conformation polymorphism ; mutation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To evaluate the role of mutations in the glucose transporter (GLUT1) gene in Japanese patients with non-insulin-dependent diabetes mellitus (NIDDM), we first conducted a population association study using the XbaI polymorphism of the gene. A polymerase chain reaction (PCR)-based assay was developed and used for the analysis. When analysed in 91 diabetic patients and 87 non-diabetic control subjects, the distribution of the genotype frequency was significantly different between the two groups (p=0.0025). The (−) allele was significantly associated with NIDDM (odds ratio 2.317, 95% confidence interval 1.425−3.768). To identify possible mutation(s) in the GLUT1 gene, which was in linkage disequilibrium with the (−) allele, all ten exons of the gene were analysed by PCR single-strand conformation polymorphism (SSCP) analysis in 53 diabetic patients with at least one (−) allele. Variant SSCP patterns were detected in exons 2, 4, 5, 7, 9 and 10. Sequence analysis revealed that all the variants represented silent mutations. One of the variants in exon 2, GCT (Ala15)→GCC(Ala), created a HaeIII restriction site. This polymorphism was common in Japanese subjects with heterozygosity of 0.36 and polymorphism information content 0.29. We conclude that the structural mutation of GLUT1 is rare and not likely to be a major genetic determinant of NIDDM in Japanese subjects. The Xbal (−) allele of the GLUT1 gene appeared to be a genetic marker of NIDDM in Japanese subjects. The possibility of the presence of mutation(s) in the regulatory region of the gene or in another locus nearby could not be excluded.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00400583
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Preparation and characterization of the LiInSe2 thin films (1983)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 1723-1727 
    Details
    ISSN: 0392-6737
    Keywords: Methods of thin-film deposition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Sono stati preparati film di LiInSe2 di tipop con il metodo di evaporazione rapida su Si di tipon e GaP di tipon. Sono state usate varie tecniche di caratterizzazione come l'analisi con raggi X, l'analisi dello scattering all'indietro di Rutherford (RBS) e la microscopia elettronica di scansione per valutare la qualità dei film. Si dimostrano le rettificazioni delle eterogiunzioni preliminari.
    Abstract: Резюме Приготовляются пленки LiInSe2 p-типа методом быстрого испарения на Sin-типа и GaPp-типа. Для оценки качества плчества пленок используются различные методики: рассеяние рентгеновских лучей, обратное резерфордовское рассеяние, сканирующая электронная микроскопия. Демонстрируется выпрямяюшее действие гетеропереходов.
    Notes: Summary p-type LiInSe2 films have been prepared by the rapid evaporation method onn-type Si andn-type GaP. Various characterization techniques such as the X-ray analysis, the Rutherford backscattering (RBS) analysis and the scanning electron microscopy were used to evaluated the quality of the films. The rectifications of the preliminary heterojunctions are demonstrated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02457857
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    Paper (German National Licenses)
    Fulltext
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