ISSN:
1420-9071
Schlagwort(e):
Pyrimidine 5′-nucleotidase (P5′N)
;
nuclear magnetic resonance
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Summary We describe here a further Japanese family with pyrimidine 5′-nucleotidase (P5′N) deficiency diagnosed using a nuclear magnetic resonance (NMR) spectrum, in Kumamoto prefecture where two families having the disease have been reported before. The specific spectra in1H-NMR of P5′N deficient erythrocytes were due to three methyl protons of CDP-choline at 3.22 ppm and to H-2, H-8 and ribose-1′ of pyrimidine nucleotide phosphate(s) in the lower fields (at 5.82 and 8.00 ppm). The other specificities in31P-NMR spectra were due to CDP-choline, CDP-ethanolamine and UDP-glucose. Those spectra were not detected in other types of hemolytic anemia.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF01975900
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