Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Neurosurgical review 4 (1981), S. 129-137 
    ISSN: 1437-2320
    Keywords: Choroid plexus papilloma ; Surgical treatment ; Surgical results ; Chorioid-Plexuspapillome ; Operative Behandlung ; Operative Ergebnisse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In der Arbeit wird über das operative Behandlungsergebnis von 27 Plexuspapillomen aus einer Serie von 28 Fällen berichtet, die zwischen 1952 und 1978 im Neurochirurgischen Institut der Universität Rom behandelt wurden. Eine Gliederung erfolgte in 2 Gruppen: a) vor 1969 und b) nach 1969 mit routinemäßiger Durchführung der Mikrochirurgie. Ventrikuläre Shunt-Operationen und Röntgentherapie wurden praeoperativ nicht vorgenommen. Eine Totalentfernung des Tumors wurde stets angestrebt und mit Ausnahme von 3 Fällen durchgeführt. In der mikrochirurgisch operierten Gruppe (1969–1978) war das Ergebnis deutlich besser. 92% wurden total extirpiert gegenüber 87% in der Gruppe a). Es verstarben postoperativ 16% gegenüber 31%. Die Spätergebnisse waren mit 67% besser als in der ersten Gruppe mit 44%. Insgesamt hatten 14 Kranke (55%) ein gutes Spätresultat mit Nachuntersuchungen nach 2 bis 27 Jahren. Die radikale Entfernung ist die Methode der Wahl in der Behandlung der Plexuspapillome. Die eigenen Erfahrungen zeigen, da– sie zu zufriedenstellendem Spätergebnis bei akzeptabler Operationsmortalität führt. Voraussetzung ist die Beherrschung der modernen Operationstechnik. Die Bedeutung der Radio-Therapie bleibt fraglich. Sie sollte ausschließlich auf maligne Fälle beschränkt bleiben.
    Notes: Summary This paper reports the results of 27 choroid plexus papillomas surgically treated, out of 28 cases observed in the authors insitute during the period 1952–1978. These were divided into two groups: a) those operated on before 1969; b) those operated on in 1969 and the following years, when microsurgical facilities were routinely employed. As a rule, neither ventricular shunting nor radiation therapy were used preoperatively. A total removal was attempted in all cases, and performed in all but three. The second group (1969–1978) showed better results as regards the number of totally removed tumours (92% against 87%), surgical deaths (16% against 31%), and long-term good results (67% against 44%). Considering both groups together, long-term good results were achieved in 15 patients (55%), followed up from 2 to 27 years. Radical operation is the treatment of choice for choroid plexus papilloma. As indicated by the author's experience, this produces satisfactory long-term results, whilst surgical mortality can be held within acceptable limits, provided that modern techniques are used properly. The value of radiation therapy, which in any event should be restricted to malignant cases, remains questionable.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1432-0533
    Keywords: Humoral immune response ; Glioma antigens ; Ultrastructural localization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Several human cell lines (normal and neoplastic glia, cerebral metastases from adenocarcinoma, fibroblasts) were incubated with sera from patients with well and poorly differentiated glioma and with sera from healthy donors and then stained with PAP complex to define and localize the antibody reaction with cell surface antigens by means of electron microscopy. The sera of glioma patients proved to contain antibodies which bound the tumor-associated antigenic determinants on the cell membranes of gliomas and of cerebral metastases from adenocarcinoma in tissue cultures. Further, absorption testing of the reactive sera on normal brain, well-differentiated astrocytoma and cultured glioblastoma cells, together with cross-reactivity experiments suggests that at least two antigens or groups of antigens are expressed on the glioma cell surface: one shared by well and poorly differentiated glioma cells and the other by poorly differentiated glioma cells and the cells of cerebral metastases from adenocarcinoma.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...