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Digitale Medien

Mitotic activity of gonadotropes in the anterior pituitary of the castrated male rat (1985)

Inoue, Kinji ; Tanaka, Shigeyasu ; Kurosumi, Kazumasa

Springer

Cell & tissue research 240 (1985), S. 271-276

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Details

ISSN: 1432-0878

Schlagwort(e): Pituitary ; Castration ; Gonadotropes ; Mitosis ; Testosterone replacement ; Rat

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie , Medizin

Notizen: Summary The proliferation of gonadotropes in the anterior pituitary of the castrated male rat was examined immunohistochemically after colchicine treatment. The results show a more than 10-fold increase in mitotic frequency in gonadotropes 1 or 2 weeks after castration, as compared with controls. This result explains the increase in the population of immunoreactive LH cells in castrated male rats. The gonadotropes decreased significantly 1 month after castration. The mitotic activity of gonadotropes was almost completely suppressed in castrates implanted with a silastic tube filled with testosterone.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00222334

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